In a nutshell This study evaluated the value of PET (positron emission tomography) scanning after first-line (primary) chemoimmunotherapy in patients with previously untreated follicular lymphoma (FL). This study concluded that PET scanning is a better imaging technique than CT (computed tomography) for assessing treatment response in these...
Read More
In a nutshell This study looked at the risk of osteonecrosis (ON – bone death/damage) as a treatment complication in children with acute lymphoblastic leukemia (ALL). The study found that older age and steroid drugs were risk factors for ON in the treatment of ALL. Some background Acute lymphoblastic leukemia (ALL) is a cancer of the bone marrow...
Read More
In a nutshell This study looked at the effect of early monitoring on disease progression and treatment cost in patients with chronic myeloid leukemia (CML). Researchers found that patients with CML who are monitored earlier may have better outcomes and lower treatment costs. Some background Chronic Myeloid Leukemia (CML) is a progressive cancer...
Read MoreIn a nutshell This study aimed to investigate the effectiveness of lenalidomide consolidation therapy after chemoimmunotherapy for patients with chronic lymphocytic leukemia. This study concluded that this regimen improves outcomes for these patients. Some background Fludarabine (Fludara) is a chemotherapy used for the treatment of chronic lymphocytic...
Read More
In a nutshell This study investigated the effectiveness of autologous stem cell transplantation (autoSCT) for patients with follicular lymphoma who experienced early treatment failure (ETF; relapse or disease progression within 2 years after first-line therapy). This study concluded that autoSCT may be an effective option for these patients. Some...
Read More
In a nutshell This study evaluated the effectiveness of rituximab (Rituxan) maintenance therapy in patients with newly diagnosed follicular lymphoma (FL). This study concluded that this therapy improves survival outcomes in these patients. Some background For patients with early (stage 1 – 2) FL, aggressive radiotherapy or...
Read MoreIn a nutshell This trial is examining the effectiveness of diet and exercise during ADT treatment for men with prostate cancer. The main outcome to be measured will be the change in body mass index (BMI, a measure of body fat that takes height and weight into account). This study is being conducted in Los Angeles and Kansas City,...
Read MoreIn a nutshell This trial is examining the effectiveness of a whole food diet for women with stable metastatic (spread) breast cancer currently undergoing treatment. The main outcomes to be measured will be the recruitment of patients approached, adherence to diet and change in symptoms and biomarkers. This study is being...
Read MoreIn a nutshell This study investigated the outcomes of surgery to lung metastasis (LM; cancer spreads to the lungs) in patients with colorectal cancer. Researchers suggested that lung surgery increases the survival of these patients. Some background Colorectal cancer is one of the major diseases seen in the US. LM appear in 5-15% of patients and...
Read More
In a nutshell This study compared the effectiveness of nilotinib (Tasigna) with high-dose imatinib (Glivec) in patients with unresponsive chronic myeloid leukemia. Researchers concluded that nilotinib may be more effective as a long-term treatment for CML when compared to imatinib. Some background Chronic myeloid leukemia is a cancer of the bone...
Read More
In a nutshell This study examined the use of the antibiotics doxycycline and ciprofloxacin to prevent infections in multiple myeloma. The study concluded that adding doxycycline to ciprofloxacin reduced the number of bacterial infections. Some background Stem cell transplantation and chemotherapy are commonly used to treat multiple myeloma. These...
Read More
In a nutshell This study investigated the cardiovascular (heart and blood vessels) safety of carfilzomib (Kyprolis) in patients with relapsed or refractory (does not respond to treatment) multiple myeloma. This study concluded that the benefits of carfilzomib outweighed its risks. Some background Multiple myeloma is a type of cancer of the bone...
Read More
