In a nutshell This article evaluates the use of Calcium and magnesium (Ca/Mg) infusions for the prevention of Oxaliplatin-related neurological side effects in patients with colorectal cancer (CRC). The main findings were that Ca/Mg helps preventing neuro-toxic side effects of Oxaliplatin-based chemotherapy regimens. Some background...
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Treating tumors of the appendix to reduce the risk of spread to the abdominal cavity
In a nutshell The present study classified tumors of the appendix and reviewed treatments that aim to prevent cancer spread to the abdominal cavity. Some background Pseudomyxoma peritonei (PMP) is a rare condition caused by the production of too much mucin (a protein that is secreted in mucus). PMP affects women more than men and symptoms...
Read MoreRising PSA levels after radiation treatment can predict prostate cancer mortality
In a nutshell This article evaluated whether the interval to biochemical failure (IBF) can be used as a prediction factor for prostate cancer mortality. The IBF was found to be the best current predictor of prostate cancer mortality in patients previously treated with radiation therapy. Some background Biochemical failure is defined...
Read MoreWhat is the preferred duration of chemotherapy? – A review of clinical trials
The aim of this paper was to identify if a longer course of chemotherapy was better than a short course. The authors look at how long patients survived with metastatic breast cancer or with no further cancer progression. Breast cancer is called metastatic when it has spread from the breast to other parts of the body such as the lymph nodes, lungs,...
Read MoreNew hormonal therapy protocol of for patients with rising PSA after radiotherapy
In a nutshell This study compared intermittent versus continuous androgen deprivation therapy (ADT) for localized (confined) prostate cancer due to prostate-specific antigen (PSA) elevation after radiotherapy. Main findings: Intermittent ADT was not inferior compared to continuous therapy with respect to survival. However, some quality of life...
Read MoreA new imaging (PET scan) agent used to locate occult prostate cancer cells when PSA is rising
In a nutshell This study examined the performance of a new radioactive tracer, 11 C-Choline, which is used for PET-CT scans, for its ability to detect prostate cancer distribution and extent after initial therapy. The tracer performed well in men with a recurrence and increased the frequency of tumor detection, compared to standard imaging...
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