In a nutshell The authors aimed to determine the link between hormone therapy and metabolic syndrome in prostate cancer patients. Some background Hormone therapy is a common treatment used in prostate cancer management. It blocks the male sex hormones active in prostate cancer, such as testosterone. In some patients hormone therapy can...
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In a nutshell The objective of this study was to determine the safe surgical margin in skin melanoma (2-4 mm thickness) and provide guidelines on the management of affected adjacent lymph nodes. Some background Melanoma is a type of cancer that starts in color-producing cells of the skin. It can grow deep into the inner layers of skin and...
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In a nutshell This article evaluated the benefits of psychology treatments for breast cancer patients with depression. Some background Many women with breast cancer also suffer from depression (22%). This can lead to a decreased quality of life and overall prognosis (treatment outcome). 'Psychodynamic psychotherapy' is a form of...
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In a nutshell The authors aimed to evaluate if the outcomes of surgery following chemotherapy are different based on the focality of breast cancer tumors. Some background Breast cancer can be characterised as 'unifocal', 'multifocal and 'multicentric'. This refers to the number of areas in which the cancer can be found...
Read MoreIn a nutshell The authors aimed to identify the best options available to identify metastatic prostate cancer. Some background Metastatic prostate cancer is cancer that has spread from the prostate gland into tissues and organs around the body. In some cases patients with metastatic cancer can become resistant to certain treatments, such as...
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In a nutshell The authors aimed to determine patient outcomes using the standard classification systems in uveal melanoma patients. Some background Uveal melanoma is a rare form of cancer that occurs in the eye. The TNM classification system can be used to determine the extent of melanoma present and can help identify the most effective...
Read MoreIn a nutshell The authors aimed to determine whether previous maintenance therapy with gemcitabine or erlotinib impaired pemetrexed treatment. Some background Maintenance therapy is the ongoing use of chemotherapy or another treatment given to help the primary treatment succeed and prevent cancer recurrence. Two drugs have been...
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In a nutshell The authors aimed to determine factors that predicted survival after return of non-small cell lung cancer. Some background Non-small cell lung cancer (NSCLC) is the most common form of lung cancer. In cases of cancer recurrence (return), NSCLC can reoccur at different sites in the body from the primary site or can be limited to a...
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In a nutshell The authors aimed to determine the effects of conventional treatment in localised prostate cancer patients with BRCA mutations. Some background BRCA mutations are mutations in the BRCA1 or BRCA2 gene (regulates cell functions). BRCA genes prevent tumors from growing. When they are mutated tumors can grow freely causing cancers such...
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In a nutshell This study investigated if measuring the levels of prostate specific antigen (PSA) after cancer therapy could indicate a cure or if the patient should be considered for long term androgen deprivation (suppression) therapy. The main finding was that lower PSA blood levels predict better survival in patients with prostate cancer. Some...
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In a nutshell The authors aimed to determine whether African Americans were more at risk of experiencing recurrent prostate cancer or complications following a radical prostatectomy. Some background Past research has shown that African American men are 60% more likely to experience prostate cancer than white men. Previously, in men who...
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In a nutshell This paper reviewed adverse events associated with treatment of breast cancer with everolimus (Afinitus). Some background Everolimus is used in postmenopausal patients for advanced breast cancer treatments. The drug has been approved for use in patients with hormone receptor positive (the presence of the estrogen...
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