In a nutshell The authors determined the benefit of combination treatment with gemcitabine (Gemzar) and oxaliplatin (Eloxatin) in hormone resistant (castration-resistant) prostate cancer. Some background Hormone therapy is a common treatment for prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone....
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In a nutshell The authors aimed to determine whether or not vitamin D could protect women against breast cancer or if it could improve a patients chances of survival. Some background Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer-related death among women. Lifestyle factors such as diet and exercise may impact...
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In a nutshell The authors analyzed the role of certain genes in predicting survival in melanoma patients treated with tremelimumab (CP-675,206). Some background In advanced melanoma (stage III/IV), cancer spreads from the skin to other parts of the body. Immunotherapy is an effective treatment for advanced melanoma. It uses the...
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In a nutshell The authors determined the significance of prostate specific antigen (PSA) levels in determining survival in prostate cancer patients with bone tumors after hormone therapy Some background Hormone therapy is a common treatment for prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone....
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In a nutshell The authors evaluated the effectiveness of radiation therapy after surgery in the management of desmoplastic melanoma (a rare kind of skin cancer). Some background Desmoplastic melanoma is a rare form of skin cancer where the cancer cells are surrounded by fibrous tissues (e.g. tissues that make up ligaments, tendons or...
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In a nutshell The authors aimed to determine whether severe skin and nail infections observed in patients with breast cancer were due to a combination-chemotherapy treatment. Some background Trastuzumab (Herceptin) is a common drug used to treat patients with human epidermal growth factor 2 positive (HER2+) breast cancer. The HER2 protein can...
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In a nutshell The authors reviewed the benefits and safety of ado–trastuzumab emtansine (Kadcyla), a treatment for metastatic breast cancer (cancer that has spread to other areas of the body). Some background Human epidermal growth factor receptor 2 positive (HER2) breast cancer depends on HER2 for growth. Treatments that target the HER2...
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In a nutshell The authors analyzed the effectiveness of radiotherapy after surgery in desmoplastic melanoma- a rare kind of skin cancer. Some background Desmoplastic melanoma is a rare form of skin cancer in which the cancer cells are surrounded by fibrous tissues (eg; tissues that make up ligaments, tendons or nerves). Local...
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In a nutshell The authors aimed to assess the effectiveness of prolonged hormone therapy to treat women with early breast cancer. Some background Tamoxifen (Nolvadex) is a type of hormone therapy used to treat breast cancer. It attaches to the estrogen receptors (surface structures that respond to estrogen hormone) present on some cancer cells...
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In a nutshell The authors evaluated a scoring system known as genomic classifier (GC) score that could indicate spread of cancer in prostate canecr patients after surgery and radiation therapy. Some background Prostate surgery and radiation therapy are common treatments in prostate cancer. Prostate surgery involves...
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In a nutshell The authors aimed to assess the overall risks of breast cancer recurrence (return of the cancer) following two types of breast cancer surgery. Some background Breast cancer treatments may include surgery; a mastectomy is the removal of the entire breast while breast-conserving surgery is the removal of the breast cancer but not the...
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In a nutshell The authors evaluated the benefits of preventive radiation therapy in patients with non-small cell lung cancer (NSCLC) who have high risk of developing brain metastases (spreading of cancer from the lungs to the brain). Some background NSCLC is the most common type of lung cancer, accounting for 85% of all lung cancers. In...
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