In a nutshell This study evaluated the impact of different durations of post-surgery chemotherapy in the treatment of locally advanced (spread to the lymph nodes) rectal cancer patients. Researchers suggested that longer post-surgery chemotherapy for stage 3 patients was associated with lower metastasis (spread to other parts of the body) rates and...
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In a nutshell This study compared early metabolic changes across different types of androgen deprivation therapy (ADT). Authors reported that some metabolic changes were more pronounced with pharmacological ADT compared to surgical ADT. Some background ADT is a type of hormone therapy commonly used to treat advanced prostate cancer. ADT targets...
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In a nutshell This study compared treatment outcomes of prostate surgery and external beam radiation therapy (EBRT) for localized prostate cancer. While mortality rates were generally very low, prostate surgery may be more suitable for men with high-risk prostate cancer. Some background Localized prostate cancer is cancer that is confined to the...
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In a nutshell This article evaluated recommendations regarding the continued care of prostate cancer survivors following successful treatment. The authors reported that regular screening, as well as proper treatments and lifestyle interventions, are important in maintaining physical and psychological health among prostate cancer survivors. Some...
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In a nutshell The authors aimed to assess and compare a number of surgical procedures used to treat and limit the risk of developing breast cancer. The study showed that there was no significant difference between contralateral prophylactic mastectomy (CPM) and breast-conserving treatment (BCT) on survival from breast cancer. Some background...
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In a nutshell The authors aimed to analyze the factors that could predict resistance to BRAF inhibitor therapy in advanced melanoma. The authors found out that levels of certain proteins and the presence of a type of immune cell could predict the occurrence of resistance. Some background In advanced melanoma (stages 3 or 4), cancer spreads...
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In a nutshell This study examined long-term side effects of radiation therapy on sexual function. Researchers report a range symptoms related to sexual function among long-term prostate cancer survivors. Some background Radiation therapy is a common treatment for localized prostate cancer. It involves directing high-energy rays at the tumor site...
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In a nutshell This review examined the benefit of adding docetaxel (Taxotere) or bisphosphonates to androgen deprivation therapy (ADT) in advanced prostate cancer. Authors reported a significant benefit when combining docetaxel with ADT in advanced metastatic prostate cancer. There is less evidence to suggest an advantage of bisphosphonates plus...
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In a nutshell This study investigated the effects of the drug denosumab (Prolia) in postmenopausal patients with hormone-receptor positive breast cancer treated with aromatase inhibitors. The study concluded that denosumab reduces the risk of bone fracture in these patients. Some background Aromatase inhibitors are hormonal therapies....
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In a nutshell The authors aimed to identify those melanoma patients having a low risk of cancer spreading to the lymph nodes. The authors found that most melanoma patients with intermediate tumor thickness (between 1.01 mm and 1.05 mm) had a similar risk of disease spread to the lymph nodes as found in patients with thin melanoma (tumor thickness of 1...
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In a nutshell This study investigated the appropriate waiting time to surgery after radiation and chemotherapy in rectal cancer patients. Researchers suggested that 56 days is the optimal waiting time for surgery after completion of radiation or chemotherapy. Some background Chemotherapy and radiation prior to surgery to remove rectal cancer has...
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In a nutshell This review summarized recent evidence on alternatives to continuous androgen deprivation therapy (CADT). Authors reported that more high-quality evidence is needed to determine overall benefits of new hormonal treatment approaches compared to ADT. Some background Androgen deprivation therapy (ADT) is a type of hormone therapy that...
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