In a nutshell This study investigated the role of stereotactic body radiotherapy (SBRT) in patients with positive margins (when the cancer is not totally removed) after chemotherapy, radiation therapy and rectal surgery. Researchers suggested that SBRT is an effective and safe treatment option. Some background Chemotherapy and radiation therapy...
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Optimal waiting time to surgery after radiation therapy in rectal cancer
In a nutshell This study investigated the optimal waiting time between radiation therapy and surgery in rectal cancer patients. Researchers suggested that a prolonged waiting time is associated with tumor shrinkage. Some background Surgery is the only curative treatment for rectal cancer. Chemotherapy and radiation therapy is the recommended...
Read MoreRe-evaluation of the tumor is beneficial for treatment planning in advanced rectal cancer patients
In a nutshell This study investigated the necessity of re-evaluation of locally advanced tumors (spread to the lymph nodes) after chemotherapy and radiation therapy. Researchers reported that re-evaluation is important to better plan treatment. Some background Chemotherapy and radiation therapy (CTRT) followed by surgery is the standard...
Read MoreOptimal waiting time to surgery after chemotherapy and radiation therapy in rectal cancer
In a nutshell This study investigated the optimal waiting time between chemotherapy and radiation therapy and surgery in rectal cancer patients. Researchers suggested that a prolonged waiting time improves response to the treatment. Some background Chemotherapy and radiation therapy (CRT) is the recommended treatment before rectal surgery....
Read MoreA Review of Prostate Cancer Prognostic Factors
Prognostic factors, including blood tests and radiographic scans, can help establish a patient’s prognosis and determine a treatment path. Experts from MD Anderson Cancer Center, Drs. Jeri Kim and Sumit Subudhi, review factors that are associate with prostate cancer and discuss research underway that could lead to more personalized...
Read MoreThe effect of delaying trastuzumab therapy
In a nutshell This study investigated the effect of delaying trastuzumab (Herceptin) therapy in patients with breast cancer. The study concluded that delays in receiving trastuzumab therapy of 6 months or more leads to decreased overall survival and relapse-free survival time. Some background Some breast cancers depend on the human epidermal...
Read MoreEmerging Prostate Cancer Immunotherapy Options
Patient advocate Jeff Folloder conducts an in-depth discussion on emerging immunotherapy approaches for advanced prostate cancer with MD Anderson Cancer Center experts, Dr. Sumit Subudhi and Dr. Jeri Kim. Walking us through developing treatments, including vaccines and checkpoint inhibitors/immune modulators, these experts refer to today as...
Read MoreA combination of surgery and chemotherapy increases survival in stage 4 colorectal cancer
In a nutshell This study investigated the impact of surgery in patients with stage 4 (spread to other areas of the body) colorectal cancer who were treated with chemotherapy. Researchers reported that surgery increased survival in these patients. Some background Prior studies have reported increased survival in patients with stage 4...
Read MoreMalnutrition caused by pre-surgery chemotherapy is associated with rectal cancer treatment outcomes
In a nutshell This study investigated the association between malnutrition caused by pre-surgery chemotherapy and radiation (CRT) and rectal cancer treatment tolerance and anastomotic leakage (AL; leakage of intestinal fluids). Researchers reported that malnutrition related to CRT is associated with treatment tolerance and AL. Some background CRT...
Read MoreIntermittent and continuous chemotherapy with docetaxel – a summary of findings
In a nutshell This review examined intermittent and continuous docetaxel (Taxotere) treatment for metastatic castration-resistant prostate cancer (mCRPC). Researchers concluded that intermittent docetaxel treatment can be a feasible treatment option in the management of mCRPC. Some background Chemotherapy with docetaxel is often the first-line...
Read MoreCan probiotics protect the intestines in patients with colorectal cancer undergoing surgery?
In a nutshell This study investigated the protective effect of probiotics in the intestine of colorectal cancer patients after surgery. Researchers suggested that probiotics are beneficial for the intestine of colorectal cancer patients who underwent surgery. Some background Colorectal cancer patients are commonly subjected to surgery as part of...
Read MoreGnRH agonists or GnRH antagonists: The risks and benefits
In a nutshell This review compared the potential risks and benefits of two hormone therapies available for androgen deprivation therapy (ADT). Authors concluded that GnRH antagonists offer a safe and effective alternative to GnRH agonists. Some background ADT is a type of hormone therapy commonly used to treat advanced prostate cancer. ADT targets...
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