In a nutshell This study investigated the outcomes of surgery to lung metastasis (LM; cancer spreads to the lungs) in patients with colorectal cancer. Researchers suggested that lung surgery increases the survival of these patients. Some background Colorectal cancer is one of the major diseases seen in the US. LM appear in 5-15% of patients and...Read More
Current treatment status-Undergoing active treatment Posts on Medivizor
In a nutshell This study compared the effectiveness of nilotinib (Tasigna) with high-dose imatinib (Glivec) in patients with unresponsive chronic myeloid leukemia. Researchers concluded that nilotinib may be more effective as a long-term treatment for CML when compared to imatinib. Some background Chronic myeloid leukemia is a cancer of the bone...Read More
In a nutshell This study examined the use of the antibiotics doxycycline and ciprofloxacin to prevent infections in multiple myeloma. The study concluded that adding doxycycline to ciprofloxacin reduced the number of bacterial infections. Some background Stem cell transplantation and chemotherapy are commonly used to treat multiple myeloma. These...Read More
Evaluating cardiovascular safety of carfilzomib in patients with relapsed or refractory multiple myeloma
In a nutshell This study investigated the cardiovascular (heart and blood vessels) safety of carfilzomib (Kyprolis) in patients with relapsed or refractory (does not respond to treatment) multiple myeloma. This study concluded that the benefits of carfilzomib outweighed its risks. Some background Multiple myeloma is a type of cancer of the bone...Read More
In a nutshell This study looked at a combination of chemotherapy and an antiangiogenic drug bevacizumab to treat patients with advanced non-small-cell lung cancer. The authors concluded that this combination may have potential to control cancer in these patients. Some background Despite the major advances in cancer treatments in recent years,...Read More
In a nutshell This study investigated respiratory side effects in patients with non-Hodgkin’s lymphoma (NHL) who received chemotherapy containing rituximab (Rituxan). This study concluded that these side effects are common and associated with increased mortality in these patients. Some background Non-Hodgkin’s lymphoma patients treated...Read More
In a nutshell This study investigated the safety and effectiveness of rituximab (Rituxan) plus bortezomib (Velcade) for patients with mantle cell lymphoma after stem cell transplant. This study concluded that this combination is a safe and effective regimen in these patients. Some background The standard treatment for younger patients with mantle cell...Read More
In a nutshell This study reviewed current and new targeted therapies for relapsed or refractory (does not respond to treatment) mantle cell lymphoma. Some background Ibrutinib (Imbruvica) remains the current standard of care for patients with mantle cell lymphoma (MCL) who relapse or develop refractory disease after initial...Read More
Is pirarubicin safer and more effective than doxorubicin in R-CHOP for diffuse large B-cell lymphoma?
In a nutshell This study compared the safety and effectiveness of two first-line chemotherapy regimens for diffuse large B-cell lymphoma. This study concluded that the R-THP-COP regimen was as effective as conventional R-CHOP for diffuse large B-cell lymphoma. Some background R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine,...Read More
Does graft versus host disease affect relapse and survival rates after a stem cell transplant in childhood leukemia?
In a nutshell This study examined the effect of graft versus host disease on relapse rates in children with acute leukemia. This study concluded that graft versus host disease may protect against relapse, but they did not see an effect on survival. Some background One complication following an allogeneic stem cell transplant (transplant using donor...Read More
In a nutshell This study was a systematic review (looking at all available and relevant evidence) of the safety and effectiveness of different treatment options for elderly patients with acute myeloid leukemia (AML). The study found that azacitidine (Vidaza) was safe and more effective than intensive chemotherapy in these patients. Some...Read More
In a nutshell This study aimed to determine whether differences in side effects reported over time in patients who had surgery or radiotherapy varied by risk group. This study found that for men with low-risk prostate cancer, radiotherapy was associated with higher sexual function scores at 3 years than surgery;...Read More