In a nutshell The authors aimed to determine the effect of erlotinib (Tarceva) in delaying treatment change in patients with progressive lung cancers with and without epidermal growth factor receptor (EGFR) mutations (changes to the cell). Some background Erlotinib is a biological therapy (drug used to stimulate or restore the body's...
Read More
In a nutshell The authors analyzed treatment options available for advanced prostate cancer. Some background At the first St. Gallen Advanced Prostate Cancer Conference leading experts met to determine the most up-to-date guidelines for the treatment of advanced prostate cancer. Advanced prostate cancer is cancer that has spread...
Read More
In a nutshell The authors interpreted the results of a phase III trial on the use of enzalutamide (Xtandi) in treating patients with metastatic (cancer that has spread) hormone-resistant (castration-resistant) prostate cancer. Some background Hormone therapy is a common treatment used in prostate cancer. It targets the male sex hormones...
Read More
In a nutshell The authors identified treatments available for men with advanced prostate cancer who were resistant to hormone therapy (castration-resistant). Some background Hormone therapy is a standard treatment for prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone. Some patients...
Read More
In a nutshell This study looked at the usefulness of radiotherapy in combination with EGFR inhibitors in patients with advanced non-small cell lung cancer (NSCLC). Some background 66% of patients with non-small cell lung cancer (NSCLC) develop stage IV cancer, where the cancer spreads to both lungs and...
Read More
In a nutshell This study examined the effectiveness of a blood test (commercially known as VeriStrat) used for predicting the benefit of EGFR inhibitors in non-small cell lung cancer. Some background The epidermal growth factor receptor (EGFR) is involved in cell growth. Increased levels of EGFR can increase non-small cell lung...
Read More
In a nutshell The authors aimed to determine the effect of enzalutamide on quality of life in patients with hormone-resistant prostate cancer after chemotherapy. Some background Hormone therapy is a common treatment used in prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone. Enzalutamide...
Read More
In a nutshell The authors aimed to determine the effectiveness of surgery for the treatment of breast cancer; specifically those within the later stages of inflammatory breast cancer. Some background Inflammatory breast cancer is a rare form of breast cancer, accounting for only 2% of all breast cancers. It is termed 'inflammatory'...
Read More
In a nutshell The aim of this study was to assess the benefits of dabrafenib (Tafinlar) and trametinib (Mekinist) as single as well as as combination therapy in advanced melanoma patients with a specific genetic status. Some background In the advanced stage of melanoma (stage III/IV), cancer spreads from the skin to other parts of...
Read More
In a nutshell The objective of this study was to evaluate the effect of erlotinib (Tarceva) in combination with pemetrexed (Alimta) and cisplatin (Platinol) in lung cancer that had spread into the brain (brain metastases). Some background Lung adenocarcinoma is the cancer of glandular cells of lungs. It is a common type of non-small cell lung...
Read More
In a nutshell The authors aimed to evaluate survival benefits of pembrolizumab (Keytruda) compared to ipilimumab (Yervoy) in advanced melanoma. Some background In the advanced stage of melanoma (stage III/IV), cancer spreads from the skin to other parts of the body. One of the standard treatments for advanced melanoma is immunotherapy that uses...
Read More
In a nutshell The authors aimed to determine the effect of orteronel in patients resistant to hormone treatment. Some background Hormone therapy is commonly used in prostate cancer treatment and involves targeting the male sex hormones active in prostate cancer, such as testosterone. In some cases patients receiving hormone therapy may become...
Read More
