In a nutshell This study examined the possible role of active surveillance (AS) as a treatment strategy for African American (AA) men whose prostate cancer is considered to be of low-risk. Some background Prostate cancer is a condition in which cells of the prostate gland grow and divide uncontrollably. In some cases, this uncontrolled growth...
Read MoreIn a nutshell This study compared the ability of two drugs, ganitumab and conatumumab, to treat patients with metastatic colorectal cancer when added to chemotherapy. Some background Cancer cells express various structures on their surface (called receptors) that may stimulate growth and help avoid destruction by the immune system. Drugs that...
Read MoreIn a nutshell This study explored whether cetuximab (erbitux) can benefit patients with unresectable colorectal liver metastases. The ability to perform surgery to remove part or all of the tumor growth in the liver (the resection rate) was compared between patients receiving cetuximab in combination with chemotherapy, to those receiving chemotherapy...
Read MoreIn a nutshell This study looked at the effect, and specifically drug related toxicities, of cabazitaxel (jevtana) plus prednisone treatment in metastatic prostate cancer patients. Some background Prostate cancer grows in response to the hormone testosterone. In order to reduce the effect of testosterone, castration is the mainstay of advanced...
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In a nutshell This study tested the effect of complete axillary lymph node removal, on survival without recurrence of the cancer (called disease free survival or DFS) in patients with breast cancer. Some background Lymph nodes are small organs which are part of the immune system. They filter fluid called lymph. Lymph can be thought of as the...
Read MoreIn a nutshell This phase III clinical trial will study which type of external radiation treatment for prostate cancer has a better side effect profile: IMRT or Proton Therapy. The details IMRT (or Intensity-modulated radiation therapy) is a type of radiation therapy commonly used to treat prostate cancer. It uses x-ray beams to target the prostate...
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In a nutshell The study presented here investigated the predictive value of pre-treatment Prostate Serum Antigen (PSA) levels in patients with recurrent localized prostate cancer as a prognostic marker for successful salvage prostate cryotherapy. The authors found that a PSA level of < 5 ng/ml is a prognostic marker for a successful treatment...
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In a nutshell The present study evaluated whether more frequent prostate-specific antigen (PSA) monitoring in patients treated for prostate cancer (PCa) was associated with earlier detection of cancer recurrence (return of the cancer) or survival. The number of PSA screenings had no effect on patient survival after treatment for PCa. Some...
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In a nutshell The present study evaluated the risk of developing ischemic heart disease in patients treated with radiotherapy for breast cancer. Patients who received radiotherapy for breast cancer are at increased risk of developing ischemic heart disease in the next 20 years. Some background Breast cancer (BCa) is the most common type of cancer...
Read MoreIn a nutshell The aim of this study was to assess how many colorectal cancer (CRC) survivors had a cardiovascular disease (CVD) and to determine the association between lifestyle factors and CVD. In this study overweight CRC survivors were more likely to suffer from CVD. Some background In the last years the number of CRC survivors has increased...
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In a nutshell This phase III trial aims to determine the benefits of using the drugs eflornithine and sulindac (Clinoril) in the prevention of high risk adenomas and secondary colorectal cancers. Researchers will look at the number of recurrences over a 3 year period while administering the drugs. The details Patients previously treated for...
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In a nutshell The present study evaluated factors associated with residual or recurrent disease in patients with colorectal adenocarcinomas developed from adenomas initially treated endoscopically. Some background A colorectal adenoma is a benign (non-cancerous) abnormal growth in the inner lining of the large intestine (colon and rectum) also...
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