In a nutshell The aim of this study was to assess the benefits of dabrafenib (Tafinlar) and trametinib (Mekinist) as single as well as as combination therapy in advanced melanoma patients with a specific genetic status. Some background In the advanced stage of melanoma (stage III/IV), cancer spreads from the skin to other parts of...
Read More
In a nutshell The objective of this study was to evaluate the safety and effectiveness of nivolumab (Opdivo) as secondary treatment in advanced melanoma. Some background In the advanced stage of melanoma (stage III/IV), cancer spreads from the skin to other parts of the body. BRAF inhibitors and immunotherapy are the standard treatments for...
Read MoreIn a nutshell The authors aimed to assess the effect of ipilimumab (Yervoy) as an additional therapy after surgery in advanced (stage III) melanoma patients who were at a high risk of relapse. Some background In the advanced stage of melanoma (stage III), cancer spreads from the skin to nearby lymph nodes (tiny, bean-shaped organs that help fight...
Read MoreIn a nutshell The authors aimed to determine the long-term outcomes of lymph node surgery in patients who experienced prostate cancer recurrence after prostate surgery. Some background Prostate surgery involves surgically removing the prostate gland in patients with prostate cancer. In some cases, following surgery, some patients may experience...
Read More
In a nutshell The objective of this study was to evaluate the effect of erlotinib (Tarceva) in combination with pemetrexed (Alimta) and cisplatin (Platinol) in lung cancer that had spread into the brain (brain metastases). Some background Lung adenocarcinoma is the cancer of glandular cells of lungs. It is a common type of non-small cell lung...
Read More
In a nutshell This article evaluated the benefits of psychology treatments for breast cancer patients with depression. Some background Many women with breast cancer also suffer from depression (22%). This can lead to a decreased quality of life and overall prognosis (treatment outcome). 'Psychodynamic psychotherapy' is a form of...
Read More
In a nutshell The authors aimed to evaluate survival benefits of pembrolizumab (Keytruda) compared to ipilimumab (Yervoy) in advanced melanoma. Some background In the advanced stage of melanoma (stage III/IV), cancer spreads from the skin to other parts of the body. One of the standard treatments for advanced melanoma is immunotherapy that uses...
Read More
In a nutshell The objective of this research was to analyze the safety and effectiveness of racotumomab (Vaxira) vaccine in advanced non-small cell lung cancer (NSCLC). Some background In the advanced stage (IIB/ IV) of NSCLC, cancer may spread throughout lungs, to adjacent lymph nodes (tiny, bean-shaped organs that help fight infections) and to...
Read More
In a nutshell The aim of this study was to determine whether the benefit from combination therapy of vandetanib (Caprelsa) and docetaxel (Taxotere) could be linked to specific biological substances in non-small cell lung cancer (NSCLC) patients. Some background In advanced stage (IIB/IV) NSCLC, cancer may spread throughout lungs and to other...
Read MoreIn a nutshell The authors aimed to determine the effects of weight in prostate cancer progression under active surveillance. Some background Active surveillance involves actively monitoring tumor growth and development in a patient without administering treatment. Prostate cancer patients undergoing active surveillance who have a high...
Read More
In a nutshell This study aimed to assess use of dacomitinib in patients with advanced non-small cell lung cancer (NSCLC) who had previously failed to respond to chemotherapy and erlotinib (Tarceva). Some background NSCLC is the most common type of lung cancer. Erlotinib and gefitinib (Iressa) are used to treat NSCLC. They...
Read MoreIn a nutshell The authors aimed to determine the effect of interleukin-2 in treating in-transit skin cancer. Some background In-transit skin cancer is cancer that has progressed into the lymph nodes (sites that hold the immune cells) from the primary site of cancer. Interleukin-2 (IL-2, Proleukin, Aldesleukin) is a man-made protein...
Read More
