In a nutshell This review compared the potential risks and benefits of two hormone therapies available for androgen deprivation therapy (ADT). Authors concluded that GnRH antagonists offer a safe and effective alternative to GnRH agonists. Some background ADT is a type of hormone therapy commonly used to treat advanced prostate cancer. ADT targets...
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Prostate Cancer and Sexuality
How does a diagnosis of prostate cancer affect intimacy? Led by patient advocate Jeff Folloder, experts across several disciplines discuss sexuality and dysfunction. The panel explores how, in one form or another, this subject affects every single advanced prostate cancer patient and his partner. Learn how communication and support through...
Read MoreErectile dysfunction and prostate surgery
In a nutshell This study investigated erectile function after prostate surgery in men with high-risk localized prostate cancer. Researchers reported high rates of erectile dysfunction following prostate surgery. Some background Surgical removal of the prostate gland is a common treatment for localized prostate cancer (cancer confined to the...
Read MoreEnzalutamide helps manage symptoms in advanced prostate cancer
In a nutshell This study examined the effects of enzalutamide (Xtandi) in improving disease-related symptoms associated with advanced metastatic prostate cancer. The researchers concluded that enzalutamide treatment is effective in managing prostate cancer-derived bone tumors and pain among men with advanced prostate cancer. Some background When...
Read MoreSearching for participants to take part in a trial investigating modifications to prostate cancer surgery
In a nutshell This phase 3 trial aims to determine the effectiveness of different ways of performing prostate cancer surgery. The main outcomes to be investigated are surgical complications and cancer recurrence. The trial is recruiting in New Jersey and New York (USA). The details Surgery to remove the prostate (also known as radical...
Read MoreLate-stage prostate cancer: Newly approved treatments examined
In a nutshell This review evaluated newly approved treatments for metastatic castration-resistant prostate cancer. Researchers concluded that a number of recently developed treatments provide a clinical benefit for men with metastatic castration-resistant prostate cancer. Some background Treatment for metastatic (cancer that has spread to...
Read MoreAlternative hormone therapy with enzalutamide – effective regardless of metastasis site
In a nutshell This study examined the effects of enzalutamide (Xtandi) with respect to the site of metastatic castration-resistant prostate cancer. Researchers concluded that enzalutamide is a safe and effective treatment for all sites of metastases studied. Some background When prostate cancer spreads outside of the prostate (also called...
Read MoreIs prostate surgery alone effective when cancer has spread to lymph nodes?
In a nutshell This study examined prostate surgery as a treatment option for prostate cancer with lymph node involvement. Researchers reported that prostate surgery alone is associated with good treatment outcomes in men with low levels of prostate cancer spread. Some background In some patients, prostate cancer cells can spread to local lymph...
Read MoreThe benefit of exercise in prostate cancer survivors
In a nutshell The authors aimed to determine the benefit of exercise in prostate cancer survivors. Results concluded that exercise had a positive effect on cancer-specific fatigue, heart health and lower body strength. Some background There are numerous types of treatment available for men with prostate cancer. The type of treatment received...
Read MoreImmunotherapy drug for treating advanced NSCLC
In a nutshell This study compared the effectiveness and safety of nivolumab (Opdivo) and docetaxel (Taxotere) for the treatment of advanced squamous-cell non-small-cell lung cancer (NSCLC). The study concluded that nivolumab is more effective and safer than docetaxel for this type of cancer. Some background PD-L1 is a protein that...
Read MoreReconsidering chemotherapy for older men with advanced prostate cancer
In a nutshell This study investigated the effects of health status in older patients with metastatic castration-resistant prostate cancer on treatment outcome with taxane-based chemotherapies. Researchers reported that taxane-based chemotherapies were associated with a significant survival benefit, regardless of age and health status. Some background...
Read MoreDealing with cancer pain: Low-dose morphine examined
In a nutshell This study compared weak opioids and low-dose morphine in providing pain relief for moderate cancer pain. Researchers concluded that low-dose morphine is more suitable as pain management for moderate cancer pain than weaker pain relievers. Some background The guidelines for cancer pain relief developed by the World Health...
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