In a nutshell This trial is examining the effectiveness of a new treatment combination for advanced Hodgkin’s lymphoma (HL). The main outcomes to be measured will be the number of patients who experience side effects and response to treatment. This study is being conducted in New York, New Jersey, and Ohio, the United States. The details The...
Read MoreIn a nutshell This trial aims to test the safety and effectiveness of adding a new drug called NKTR-214 to treatment with nivolumab (Opdivo) is better than just using nivolumab alone. The main outcomes that will be measured are how many people respond to treatment, how long the patients go without cancer growing or spreading, and overall...
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In a nutshell This study looked at the risk of reactivating hepatitis B (HBV) infection in patients with lymphoma treated with obinutuzumab (Gazyva) or rituximab (Rituxan). Researchers found that HBV infection was reactivated in some of these patients but treatment options are available. Some background Lymphoma is a cancer of the immune system....
Read MoreIn a nutshell The study looked at the safety and effectiveness of adding dexamethasone (Decadron) to lenalidomide (Revlimid) in previously untreated patients with chronic lymphocytic leukemia (CLL). Researchers concluded that lenalidomide plus dexamethasone is an effective treatment for CLL. Some background Chronic lymphocytic leukemia (CLL) is a...
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In a nutshell This study wanted to find out how the timing of radiation therapy affected survival in patients with lung cancer who underwent surgery. The study found that there was no difference in survival based on timing of radiation therapy. Some background There are a number of options for treatment of non-small cell lung cancer. Surgery...
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In a nutshell This study evaluated the value of PET (positron emission tomography) scanning after first-line (primary) chemoimmunotherapy in patients with previously untreated follicular lymphoma (FL). This study concluded that PET scanning is a better imaging technique than CT (computed tomography) for assessing treatment response in these...
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In a nutshell This study wanted to see if using a scalp cooling cap during chemotherapy stopped patients with breast cancer from losing their hair. The study found that scalp cooling help prevent the patients from losing their hair. Some background An unfortunate side effect of chemotherapy for breast cancer is that often, patients lose their hair. It...
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In a nutshell This study evaluated the effectiveness of maintenance therapy with rituximab (Rituxan) in elderly patients with newly diagnosed follicular lymphoma (FL). This study concluded that maintenance rituximab treatment improved survival outcomes in these patients in a real-world setting. Some background Chemoimmunotherapy containing rituximab...
Read MoreIn a nutshell This study aimed to investigate the long-term effects of two treatment combinations for advanced prostate cancer. This study found that surgery and radiotherapy had improved overall survival in comparison with radiotherapy plus androgen deprivation therapy (ADT) in these patients, but with higher rates of side-effects. Some background...
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In a nutshell This study evaluated the effectiveness of short-course (2 cycles) ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine) chemotherapy with interim PET scanning in previously untreated patients with early-stage (stage 1 – 2) Hodgkin’s lymphoma (HL). This study concluded that short-course ABVD was effective in the majority of...
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In a nutshell This article reviewed treatment guidelines that have been recommended for patients with early-stage prostate cancer. Some background This analysis of existing treatment guidelines was done by the leading experts in prostate cancer research. They have made recommendations on the treatment of early-stage prostate cancer. Methods...
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In a nutshell This study aimed to investigate the effectiveness of obinutuzumab and venetoclax after bendamustine treatment in patients with chronic lymphocytic leukemia (CLL). This study concluded that this sequence of treatment caused no unexpected side effects. It also concluded that the outcomes were comparable to established therapies for CLL. Some...
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