In a nutshell This study is evaluating the effectiveness of brentuximab vedotin (Adcetris) plus chemotherapy for children with advanced Hodgkin lymphoma (HL). The main outcome to be measured will be the number of patients who respond to treatment. The details Brentuximab vedotin is being tested to treat children who have advanced HL. Brentuximab...
Read MoreCurrent treatment status-Did not start treatment yet Posts on Medivizor
Further surgery or non-surgical options for patients with remaining breast cancer after surgery
In a nutshell This study evaluated whether treating breast cancer that has not been completely removed with more surgery was more effective than non-surgical options such as chemotherapy. This study found that there was no difference in outcomes between treating with further surgery versus treating with a non-surgical option. Some...
Read MoreSearching for patients with early-stage HER2+ breast cancer to trial a new treatment regime
In a nutshell This study will examine how safe and effective the medication atezolizumab (Tecentriq) is in combination with other anti-cancer medicines for treating early stage HER2+ breast cancer. The main outcome that will be measured is how many patients completely respond to treatment, with no trace of the cancer remaining. The details...
Read MoreSearching for patients with HIV-positive lymphoma to test EPOCH-R chemotherapy
In a nutshell This study is evaluating the effectiveness of EPOCH-R chemotherapy for patients with non-Hodgkin's lymphoma (NHL) who are HIV-positive. The main outcome to be measured will be survival without cancer growing or spreading. This study is recruiting in Bethesda, Maryland, United States. The details Patients with NHL who are...
Read MoreEvaluating PCR therapy for previously untreated indolent non-Hodgkin’s lymphoma
In a nutshell This study evaluated the long-term effectiveness and safety of a new chemotherapy regimen in patients with previously untreated indolent (painless) non-Hodgkin’s lymphoma (NHL). This study concluded that this regimen is effective and well-tolerated for these patients. Some background There are three common types of painless NHL....
Read MoreSearching for patients to try a new combination of treatments for Hodgkin lymphoma.
In a nutshell This trial is investigating the effects of AVD [doxorubicin (Adriamycin), vinblastine (Velban), and dacarbazine (DTIC)] with brentuximab vedotin (Adcetris) induction chemotherapy, plus nivolumab (Opdivo) for Hodgkin lymphoma (HL). The main outcome to be measured is survival without cancer worsening 3 years after treatment. The details...
Read MoreLooking for patients with prostate cancer to test a vaccine
In a nutshell This phase 2 trial will investigate the safety and effectiveness of a prostate cancer vaccine. The main outcome will be the rate of prostate cancer progression. The details Prostate cancer (PC) is cancer the originates in the prostate gland (PG). PC is very common, however, most men will recover from it. The progression of PC is...
Read MoreComparing urinary function after robotic surgery or radical perineal surgery for early stage prostate cancer
In a nutshell This study aimed to evaluate two less invasive surgeries in the treatment of localized prostate cancer (PCa). This study found that there was no difference in urinary symptoms 12 months after the two methods. Some background Prostate surgery is a treatment option for prostate cancer (PCa). This surgery can be carried out by classic...
Read MorePredicting treatment success in early RA: can biomarkers predict methotrexate response?
In a nutshell This study investigated if biomarkers (BMs) can predict the response to methotrexate (MTX) in early rheumatoid arthritis (RA). They found that the level of BMs at baseline could predict the success of MTX treatment. Some background Rheumatoid arthritis (RA) is a condition caused by inflammation. This leads to painful swelling...
Read MoreEvaluating A+AVD for patients with newly diagnosed advanced Hodgkin lymphoma
In a nutshell This study evaluated the safety and effectiveness of brentuximab vedotin (Adcetris) plus chemotherapy for patients with advanced (stage 3 – 4) Hodgkin’s lymphoma (HL). This study concluded that this treatment is effective for these patients. Some background The most commonly used frontline chemotherapy regimen for advanced HL...
Read MoreLooking for men with newly diagnosed prostate cancer to test an immune based therapy, Sipuleucel-T
In a nutshell This study evaluates the effectiveness of an immunotherapy in the treatment of newly diagnosed prostate cancer. The main outcome to be measured in this trial is the number of patients whose cancer does not progress within 3 years after immunotherapy injection. This trial is taking place in many sites across the USA. The details...
Read MoreReviewing treatment strategies for early-stage Hodgkin lymphoma
In a nutshell This article reviews treatment strategies for patients with early-stage (stage 1 – 2) Hodgkin lymphoma (HL). Some background One of the main treatment goals for patients with HL is to improve long-term outcomes. However, many patients experience complications decades after initial treatment. These may include secondary cancer...
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