In a nutshell This study reported on the long-term outcome of intensive immunochemotherapy and stem cell transplantation in patients with mantle cell lymphoma. This study concluded that long-term results were encouraging but highlighted the need for personalized treatment options. Some background The combination of intensive chemotherapy combined...
Read MoreCurrent treatment status-Did not start treatment yet Posts on Medivizor
Can neoadjuvant therapy influence other treatments for breast cancer?
In a nutshell This study aimed to investigate whether neoadjuvant systemic therapy (NST) influenced the eligibility of HER2 positive breast cancer patients to undergo breast conserving therapy (BCT). This study concluded the use of NST can result in patients who are non-eligible for BCT converting to patients that are eligible for BCT. Some...
Read MoreExamining lenalidomide as a maintenance therapy for multiple myeloma
In a nutshell This study examined whether lenalidomide (Revlimid) is effective as a maintenance therapy after first-line treatment for multiple myeloma. Researchers concluded that lenalidomide significantly delayed disease progression. Some background High-dose chemotherapy followed by stem cell transplantation is a standard treatment for newly...
Read MoreWhat is the most effective induction therapy for multiple myeloma patients preparing for stem cell transplantation?
In a nutshell This study compared two induction therapy regimens before high-dose chemotherapy and stem cell (immature blood cell) transplantation (SCT) in patients with multiple myeloma. The authors concluded that the combination of bortezomib (Velcade), thalidomide (Thalomid), and dexamethasone (Ozurdex) was more effective than bortezomib,...
Read MoreIs stem cell transplantation always necessary for mantle cell lymphoma?
In a nutshell This study reported the long-term outcomes of patients with mantle cell lymphoma treated with intense chemoimmunotherapies, without stem cell transplantation (SCT). This study concluded that this treatment combination, without SCT, was safe and effective. Some background Mantle cell lymphoma (MCL) is an aggressive form of non-Hodgkin...
Read MoreTreatment strategies for early-stage follicular lymphoma
In a nutshell This study compared the outcomes associated with various treatments for early-stage follicular lymphoma. This study concluded that survival was similar with watchful waiting compared to other early treatments. Some background Follicular lymphoma (FL) is the most common form of slow-growing non-Hodgkin lymphoma. Less than 20% of...
Read MoreIs active surveillance suitable for prostate cancer patients regardless of age?
In a nutshell This study aimed to investigate the relationship between patient age and active surveillance outcomes in prostate cancer (PC). This study concluded that younger patients undergoing AS were less likely to see an increased Gleason score and progression. Some background Early stage PC that has not yet spread is often not treated...
Read MoreA comparison of biological treatments for juvenile arthritis
In a nutshell This study compared effectiveness and safety of the biological drugs etanercept (Enbrel), adalimumab (Humira), and tocilizumab (Actemra) in patients with juvenile idiopathic arthritis (JIA). The authors concluded that there were no significant differences in effectiveness. Some background Juvenile idiopathic arthritis (JIA) is a...
Read MoreLooking for patients to test whether TNF inhibitor treatment can lower cardiovascular risk
In a nutshell The aim of this clinical trial is to determine the connection between inflammation, lipids (fats), and cardiovascular disease in rheumatoid arthritis. The main outcome to be measured is the rate of blood flow through the heart before and after treatment with certolizumab (Cimzia). The details Cardiovascular (CV) risk is known...
Read MoreAltering drug dosage during chemotherapy can decrease toxic side effects for patients with NSCLC
In a nutshell This trial examined whether altering the recommended dose of chemotherapy drugs during treatment was beneficial to patients. This trial concluded that altering doses of paclitaxel (Taxol) during chemotherapy could be beneficial to reduce neuropathy in patients with advanced non-small-cell lung cancer. Some...
Read MoreSurgery to treat stage 1 non-small cell lung cancer
In a nutshell This trial examined different surgical techniques to treat early stage non-small-stage lung cancer. The authors concluded that there was no difference in effectiveness between three different surgical techniques for patients with early stage NSCLC. Some background Early-stage non-small cell lung cancer (NSCLC) is commonly...
Read MoreUse of ABVD chemotherapy in children and young adults
In a nutshell The authors looked at the use of ABVD chemotherapy in children and young adults. They concluded that ABVD is an effective treatment in both age groups. Some background Hodgkin lymphoma (HL) is one of the most common cancers in children and young adults. HL is generally considered curable in children and young adults, and outcomes are...
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