In a nutshell This trial is examining the effectiveness of pulsed electromagnetic field (PEMF) or an anesthetic bupivacaine in lowering the incidence of chronic pain after surgery. The main outcome to be measured will be the incidence of chronic pain after each treatment. This study is being conducted in New York City. The...
Read MoreCurrent treatment status-Did not start treatment yet Posts on Medivizor
How safe and effective is R-CHOP as a first-line treatment for patients with FL in the long-term?
In a nutshell This study compared the safety and effectiveness of R-CHOP (rituximab combined with cyclophosphamide, doxorubicin, vincristine, prednisone) to CHOP-RIT (CHOP followed by iodine-133-tositumomab, Bexxar) as a first-line treatment for follicular lymphoma (FL) patients. This study concluded that immunochemotherapy should remain the standard...
Read MoreWeekly carfilzomib, cyclophosphamide, and dexamethasone in multiple myeloma
In a nutshell This paper studied the outcome of weekly carfilzomib, cyclophosphamide, and dexamethasone in patients with newly diagnosed multiple myeloma who cannot be treated with transplant. The authors concluded that this combination was effective in these patients. Some background Multiple myeloma is a cancer of the plasma cells of the blood....
Read MoreCombining systemic and local therapy – is there a benefit for patients with advanced non-small-cell lung cancer?
In a nutshell This study looked at different combinations of local and systemic therapy for treating patients with advanced non-small-cell lung cancer (NSCLC). The authors concluded that this type of aggressive combination therapy could improve survival rates of these patients. Some background Roughly half of patients with NSCLC are not diagnosed...
Read MoreOxaliplatin in the treatment of colorectal cancer in elderly patients
In a nutshell This study investigated the safety of oxaliplatin to treat colorectal cancer in elderly patients. Researchers suggested that oxaliplatin treatment is associated with neuropathy (numbness of arms or legs) in these patients. Some background Colorectal cancer is one of the most common forms of cancer among the elderly....
Read MoreSide effects of treatment in multiple myeloma
In a nutshell This paper reviewed the side effects of drugs used in the treatment of multiple myeloma. Some background Treatment for multiple myeloma includes different groups of medications. Immunomodulatory drugs work by changing the function of the immune systems. Proteasome inhibitors work by blocking the breakdown of proteins that are...
Read MoreDaratumumab plus bortezomib, melphalan, and prednisone for newly diagnosed myeloma
In a nutshell This paper studied the effect of daratumumab together with bortezomib, melphalan, and prednisone in patients with newly diagnosed multiple myeloma. The study found that the addition of daratumumab improved survival. Some background Multiple myeloma is a cancer of the plasma cells of the blood. Daratumumab (Darzalex) is a drug...
Read MoreFirst-line tyrosine kinase inhibitors: Comparing bosutinib and imatinib
In a nutshell This study compared the effectiveness of two types of tyrosine kinase inhibitors – imatinib (Gleevac) and bosutinib (Bosulif) – for chronic myeloid leukemia (CML). Researchers reported higher treatment response rates with bosutinib than with imatinib. Some background Many patients with CML...
Read MoreEarly outcomes of proton therapy after chemotherapy
In a nutshell This study examined outcomes for patients with Hodgkin lymphoma receiving chemotherapy followed by proton therapy. Researchers reported good disease control and a low rate of side effects at 3 years. However, continued follow-up is needed. Some background The combination of chemotherapy and radiation therapy provides the best...
Read MoreComparing transplant options for patients with acute myeloid leukemia and acute lymphoblastic leukemia
In a nutshell This study aimed to compare unrelated donor umbilical cord blood transplant and unrelated hematopoietic stem cell transplant in adult and pediatric patients with acute myeloid leukemia and acute lymphoblastic leukemia. This study concluded that unrelated donor umbilical cord blood transplants could be used more often as a treatment...
Read MoreImpact of delayed sentinel lymph node biopsy in early melanomas
In a nutshell This study investigated the impact of the time between diagnosis and sentinel lymph node biopsy (SLNB) in melanoma outcomes. Researchers suggested that no negative effects are associated with delayed SLNB. Some background SLNB is a procedure used to detect lymph node metastasis (spread disease) in melanoma patients. The...
Read MorePartial gland ablation versus prostate surgery in men with low- or intermediate-risk prostate cancer
In a nutshell The authors aimed to determine patient outcomes following partial gland ablation compared to robot-assisted radical prostate surgery in men with low- and intermediate- risk prostate cancer. The authors concluded that men with cancer confined to the prostate benefited from partial gland ablation, as it was more successful with fewer side...
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