In a nutshell This study assessed the safety and effectiveness of RVD (lenalidomide, bortezomib, dexamethasone) in patients with multiple myeloma before a stem cell transplant (SCT) in a real-life setting (outside of clinical trials). This study concluded that this treatment was safe and effective for these patients. Some background Multiple myeloma...
Read MoreCurrent treatment status-Did not start treatment yet Posts on Medivizor
Can FDG-PET/CT scanning predict treatment outcomes in diffuse large B-cell lymphoma?
In a nutshell This study evaluated whether FDG-PET/CT imaging during treatment helped predict outcomes for patients with diffuse large B-cell lymphoma (DLBCL). The authors concluded that mid-treatment imaging might help determine disease status rather than guide treatment decisions. Some background DLBCL is the most common type of...
Read MoreLooking for patients with metastatic triple-negative breast cancer to trial experimental vaccine with biological therapy
In a nutshell This trial is examining the most beneficial dose of an experimental AE37 vaccine when used with biological therapy pembrolizumab (Keytruda). The main outcomes to be measured are the maximum safest dose of AE37 and objective response rate. This study is recruiting in Illinois and West Virginia, US. The details Triple-negative...
Read MoreEvaluating the TLI-ATG conditioning regimen before allogeneic stem cell transplantation in patients with lymphoma or leukemia
In a nutshell This study evaluated the safety and effectiveness of total lymphoid irradiation and anti-thymocyte globulin (TLI-ATG) conditioning before stem cell transplantation (SCT) in patients with lymphoma or leukemia. This study concluded that this regimen was well-tolerated and effective, especially for patients who had multiple lines of prior...
Read MoreIbrutinib – rituximab vs chemoimmunotherapy for chronic lymphocytic leukemia
In a nutshell This study aimed to investigate the effectiveness of ibrutinib–rituximab treatment compared to standard chemoimmunotherapy in patients aged 70 or younger with previously untreated chronic lymphocytic leukemia (CLL). This study concluded that the ibrutinib–rituximab regimen provided...
Read MoreCan radioimmunotherapy help make chemotherapy more effective for patients with follicular lymphoma?
In a nutshell This study examined if Y-90 (Zevalin) improved the effectiveness of chemotherapy for follicular lymphoma. The authors found that Y-90 improved the effectiveness of chemotherapy and was generally safe. Some background Follicular lymphoma (FL) is a type of non-Hodgkin lymphoma. It is usually treated with chemotherapy. BR...
Read MoreEvaluating outcomes for patients with follicular lymphoma after rituximab maintenance therapy
In a nutshell This study looked at long-term outcomes for patients with follicular lymphoma after rituximab (Rituxan) maintenance therapy. This study concluded that rituximab maintenance helped improve long-term survival without disease progression compared to no treatment. Some background Follicular lymphoma (FL) is the second most common type of...
Read MoreLooking for patients with prostate cancer to test a type of radiation treatment
In a nutshell This phase 3 trial will compare the safety and effectiveness of hypofractionated radiotherapy (HF-RT) to standard radiotherapy (RT). The main outcomes will be the number of grade 2 side effects and disease control. This trial is recruiting in Houston, Texas, United States. The details Radiation therapy (RT) is a...
Read MoreSearching for patients to try combinations of treatments for newly diagnosed multiple myeloma.
In a nutshell This study is looking for patients with newly diagnosed multiple myeloma (MM) to try different treatment regimens. The main outcome that will be measured is the number of patients who do not experience cancer worsening after treatment. This trial is recruiting in Chicago, Illinois, United States. The details There are several...
Read MoreCarfilzomib, melphalan and prednisone treatment for newly diagnosed elderly patients with multiple myeloma
In a nutshell This study aimed to investigate the maximum tolerated dose of carfilzomib plus melphalan and prednisone (KMP regimen) in patients with newly diagnosed elderly patients with multiple myeloma (MM). This study concluded that the maximum tolerated dose of carfilzomib was...
Read MoreEvaluating SCR chemotherapy for patients with non-Hodgkin’s lymphoma
In a nutshell This study evaluated the effectiveness and safety of a new chemotherapy regimen for patients with non-Hodgkin’s lymphoma (NHL). This study concluded that this regimen was highly effective for these patients, but was associated with some side effects. Some background For patients with NHL, age is one determining factor for treatment...
Read MoreSearching for patients with untreated chronic lymphocytic leukemia to test combined immunotherapy
In a nutshell This phase 2 study is evaluating the effectiveness of a new combination therapy for chronic lymphocytic leukemia (CLL). The main outcome to be measured will be the number of patients who have a complete disappearance of all signs of cancer. This study is recruiting in Rochester, New York, US. The details Typical treatments for CLL...
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