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Evaluating the long-term effectiveness and safety of fixed-duration combination of ibrutinib plus obinutuzumab-based immunochemotherapy for patients with chronic lymphocytic leukemia.

Evaluating the long-term effectiveness and safety of fixed-duration combination of ibrutinib plus obinutuzumab-based immunochemotherapy for patients with chronic lymphocytic leukemia.

Posted by on Aug 27, 2023 in Leukemia | 0 comments

In a nutshell This study reported the long-term effectiveness and safety of the fixed-duration combination of ibrutinib (Imbruvica) plus obinutuzumab (Gazyva)–based immunochemotherapy for patients with previously untreated chronic lymphocytic leukemia (CLL). The data showed that a fixed-duration combination of ibrutinib plus obinutuzumab-based...

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Evaluating the effectiveness and safety of penpulimab in patients with relapsed or refractory classical Hodgkin lymphoma.

Evaluating the effectiveness and safety of penpulimab in patients with relapsed or refractory classical Hodgkin lymphoma.

Posted by on Feb 5, 2023 in Hodgkin's lymphoma | 0 comments

In a nutshell This study evaluated the effectiveness and safety of penpulimab (AK105) for the treatment of patients with relapsed or refractory (r/r) classical Hodgkin lymphoma (cHL). The data showed that penpulimab was effective and safe with manageable side effects in these patients. Some background Classical Hodgkin lymphoma (cHL) is a cancer of...

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Evaluating the effectiveness and safety of mFOLFOXIRI chemotherapy with or without radiotherapy before surgery in patients with locally advanced rectal cancer

Evaluating the effectiveness and safety of mFOLFOXIRI chemotherapy with or without radiotherapy before surgery in patients with locally advanced rectal cancer

Posted by on Jan 26, 2023 in Colorectal cancer | 0 comments

In a nutshell This study evaluated the effectiveness and safery of administering modified (m) FOLFOXIRI (folinic acid, fluorouracil, irinotecan, oxaliplatin) chemotherapy with or without radiotherapy before surgery in patients with locally advanced rectal cancer (LARC). The results showed that this treatment was safe and improved survival without disease...

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Evaluating the effectiveness and safety of zanubrutinib versus bendamustine plus rituximab in untreated patients with chronic lymphocytic leukemia and small lymphocytic lymphoma.

Evaluating the effectiveness and safety of zanubrutinib versus bendamustine plus rituximab in untreated patients with chronic lymphocytic leukemia and small lymphocytic lymphoma.

Posted by on Dec 31, 2022 in Leukemia | 0 comments

In a nutshell This study investigated the effectiveness and safety of zanubrutinib (Brukinsa) versus bendamustine (Treanda) plus rituximab (Rituxan) in untreated patients with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). The data showed that zanubrutinib significantly improved the survival without cancer worsening versus...

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Evaluating the effectiveness and safety of zanubrutinib versus bendamustine plus rituximab in untreated patients with chronic lymphocytic leukemia and small lymphocytic lymphoma.

Evaluating the effectiveness and safety of zanubrutinib versus bendamustine plus rituximab in untreated patients with chronic lymphocytic leukemia and small lymphocytic lymphoma.

Posted by on Dec 31, 2022 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This study investigated the effectiveness and safety of zanubrutinib (Brukinsa) versus bendamustine (Treanda) plus rituximab (Rituxan) in untreated patients with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). The data showed that zanubrutinib significantly improved the survival without cancer worsening versus...

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Long-term safety and effectiveness of acalabrutinib with or without obinutuzumab versus obinutuzumab plus chlorambucil in patients with chronic lymphocytic leukemia

Long-term safety and effectiveness of acalabrutinib with or without obinutuzumab versus obinutuzumab plus chlorambucil in patients with chronic lymphocytic leukemia

Posted by on Apr 26, 2022 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the long-term safety and effectiveness of acalabrutinib (Calquence) with or without obinutuzumab (Gazyva) versus obinutuzumab with chlorambucil (Leukeran) in patients with chronic lymphocytic leukemia (CLL) that have never received treatment (treatment-naive).  This study concluded that the...

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Fertility preservation for young people with blood cancer

Fertility preservation for young people with blood cancer

Posted by on Oct 31, 2021 in Leukemia | 0 comments

In a nutshell This review looked at options to preserve future fertility for young people diagnosed with blood cancer.  Some background For teens and young adults, blood and bone marrow cancers are one of the most common types of cancer. These include Hodgkin lymphoma (HL), non-Hodgkin lymphoma (NHL), and acute leukemia. Fortunately, blood...

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Evaluating short-course radiation therapy followed by chemotherapy for patients with rectal cancer.

Evaluating short-course radiation therapy followed by chemotherapy for patients with rectal cancer.

Posted by on Oct 9, 2021 in Colorectal cancer | 0 comments

In a nutshell This study evaluated short-course radiation therapy (RT) followed by chemotherapy as a non-surgical treatment of patients with rectal cancer (RC). The data showed that treatment with short-course RT and chemotherapy is safe and effective for these patients. Some background Colorectal cancer (CRC) is one of the most common types of...

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Evaluating the effectiveness and safety of total neoadjuvant therapy versus standard neoadjuvant chemoradiotherapy for locally advanced rectal cancer.

Evaluating the effectiveness and safety of total neoadjuvant therapy versus standard neoadjuvant chemoradiotherapy for locally advanced rectal cancer.

Posted by on Jul 17, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of total neoadjuvant therapy (TNT) versus standard neoadjuvant chemoradiotherapy (CRT) for the treatment of patients with locally advanced rectal cancer (LARC). The data showed that TNT was associated with improved outcomes compared with standard CRT for these patients. Some background...

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Does focal laser ablation improve outcomes in the long-term for patients with prostate cancer?

Does focal laser ablation improve outcomes in the long-term for patients with prostate cancer?

Posted by on Jun 30, 2021 in Prostate cancer | 0 comments

In a nutshell The study aimed to understand the long-term outcomes of focal laser therapy (FLT) in patients with prostate cancer. The study showed that this treatment has long-term survival without recurrence in certain patients.   Some background Surgical removal of the prostate gland is often recommended as a treatment for...

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Is chemoradiotherapy before surgery needed for patients with stage II-III colorectal cancer?

Is chemoradiotherapy before surgery needed for patients with stage II-III colorectal cancer?

Posted by on Mar 14, 2021 in Colorectal cancer | 0 comments

In a nutshell This study evaluated whether chemoradiotherapy (CRT) before surgery improves the outcomes of patients with stage II-III colorectal cancer (CRC). The study found that CRT before surgery may not be needed in certain patients with low-risk disease. Some background CRC is the third most common cancer worldwide. The standard therapy for...

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