In a nutshell The authors aimed to determine the benefits and drawbacks of prostate cancer treatment in patients who suffer from pre-treatment urinary problems. The authors concluded that patients with pre-treatment urinary problems benefitted from prostate surgery. Some background Prostate surgery involves surgically removing the prostate...
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In a nutshell This study compared the safety and effectiveness of external beam radiation therapy (EBRT) and hypofractioned EBRT (H-EBRT) for localized prostate cancer. Researchers reported no differences in survival or disease recurrence rates between high H-EBRT and EBRT. Some background Radiation therapy is a common treatment for localized...
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In a nutshell The main objective of this study was to review all data available on focal radiotherapy (FRT) for men with early prostate cancer. The authors concluded that FRT was an option in early prostate cancer but may not be as effective in intermediate-risk tumors. Some background Radiation therapy is an important part of prostate cancer...
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In a nutshell This study examined the relationship between androgen deprivation therapy (ADT) and the risk of falls. Authors present preliminary evidence suggesting that patients receiving ADT may be at increased risk of falls. Some background ADT is a type of hormone therapy commonly used to treat advanced prostate cancer. By reducing the levels...
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How does prostate cancer work? With Andrew Schorr as host, Dr. Russell Szmulewitz of the University of Chicago Medical Center gives a short description of the endocrinology of prostate cancer and provides an overview of hormonal therapies. Listen as Dr. Szmulewitz examines the changing treatment paradigm including risks and...
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In a nutshell This study examined the effect of androgen deprivation therapy (ADT) on clinical depression. Authors reported that ADT increased the risk of depression and the need for psychiatric treatment. The risk of depression increased with duration of ADT. Some background ADT is a type of hormone therapy commonly used to treat prostate cancer....
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In a nutshell This study examined the effectiveness of high-intensity focused ultrasound (HIFU) in treating unilateral prostate cancer (only affecting one side). Authors reported good cancer control and a low rate of side effects. Some background Advances in cancer screening methods have led to earlier diagnoses of prostate cancer. Most are...
Read MoreIn a nutshell This review evaluated recent evidence on the management of high-risk prostate cancer. Primary treatment options for high-risk prostate cancer were generally associated with good effectiveness, but authors advised that risk assessment is in need of refinement and standardization. Some background About 15% of men with prostate cancer...
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In a nutshell This study examined outcomes of different treatment options among older men (aged 70 or older) with high-risk prostate cancer. Authors reported lower disease recurrence rates for prostate surgery compared to radiation and radiation with hormone therapy. Some background Prostate surgery and radiation therapy are both common treatment...
Read MoreIn a nutshell This study compared external beam radiation therapy (EBRT) and hypofractioned EBRT (H-EBRT) for low-risk localized prostate cancer. Researchers reported no differences in disease progression or survival. However, an increase in side effects was observed with H-EBRT. Some background Radiation therapy is a common treatment for...
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In a nutshell This study examined the safety and effectiveness of androgen deprivation therapy (ADT) plus docetaxel (Taxotere) compared to ADT alone for metastatic prostate cancer. Researchers reported increased progression-free survival and overall survival when ADT was combined with docetaxel. Some background ADT is a type of hormone therapy...
Read MoreIn a nutshell This study compared the safety and effectiveness of two forms of imaging-guided radiation techniques for prostate cancer. Researchers reported more favorable outcomes with intensity modulated radiation therapy (IMRT) than with 3-dimensional conformal radiation therapy (3DCRT). Some background Radiation therapy is a common treatment...
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