In a nutshell This paper studies the effect of killer cell immunoglobulin-like receptor genes on methotrexate (Trexall) treatment. Some background Rheumatoid arthritis is an inflammatory disorder involving the immune system. Natural killer cells are part of the immune system and have been reported to contribute to rheumatoid arthritis....
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In a nutshell This study examined the safety and efficacy of a tocilizumab (Actemra) injection in rheumatoid arthritis. Some background Rheumatoid arthritis is an autoimmune disorder, meaning the body’s immune system begins attacking healthy tissue in the same way it attacks bacteria or viruses. The main treatment for rheumatoid arthritis is...
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In a nutshell This review evaluated recent research into genetic predictors of response to treatments with methotrexate (MTX) and TNF-blocking agents. Some background The treatment of rheumatoid arthritis (RA) is based on drugs which modify the behavior of the immune system and reduce the extent of inflammation. Methotrexate (MTX), a commonly used...
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In a nutshell This review discusses the choice of second-line treatment when patients fail to respond to a first tumor necrosis factor (TNF)-inhibitor in rheumatoid arthritis. Some background Common treatments for rheumatoid arthritis (RA) include biologic disease-modifying antirheumatic drugs (DMARDs), such as tumor necrosis factor...
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