In a nutshell This study compared weak opioids and low-dose morphine in providing pain relief for moderate cancer pain. Researchers concluded that low-dose morphine is more suitable as pain management for moderate cancer pain than weaker pain relievers. Some background The guidelines for cancer pain relief developed by the World Health...
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In a nutshell This study compared weak opioids and low-dose morphine in providing pain relief for moderate cancer pain. Researchers concluded that low-dose morphine is more suitable as pain management for moderate cancer pain than weaker pain relievers. Some background The guidelines for cancer pain relief developed by the World Health...
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In a nutshell The authors evaluated the safety and effectiveness of nab-paclitaxel (Abraxene), a chemotherapy, in patients with advanced melanoma. The authors found that nab-paclitaxel was safe, effective, and provided favorable outcomes. Some background In advanced melanoma, cancer spreads from the skin to other parts of the body. This is called...
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In a nutshell This study examined the benefit of enzalutamide (Xtandi) in treating patients with advanced prostate cancer requiring chemotherapy. Researchers concluded that enzalutamide treatment results in delayed disease progression and increased overall survival. Some background Hormone therapy is commonly used to treat prostate cancer. By...
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In a nutshell This study determined the benefit of combined hormone-chemotherapy in the treatment of metastatic prostate cancer. Researchers concluded that combination therapy resulted in significantly longer overall survival. Some background Androgen deprivation therapy (ADT) is a type of hormone therapy that targets androgens, the male sex...
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In a nutshell This study compared the efficacy of antitumor drugs nivolumab (Opdivo) and docetaxel (Taxotere) in the treatment of advanced non-small-cell lung cancer (NSCLC). The study concluded that nivolumab has better activity in advanced nonsquamous NSCLC which express the ligand PD-L1 and has a safer toxicity profile overall than docetaxel. Some...
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In a nutshell The authors evaluated the effect of a type of immunotherapy in treating advanced melanoma. This immunotherapy was found to be safe and effective. Some background In advanced melanoma (stage 3 or 4), the cancer spreads to the other parts of the body. This is called metastasis. Immunotherapy is a promising treatment option...
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In a nutshell The authors reviewed different treatment options for melanoma that spread to brain. This included surgery and combination treatment, among others, and scope for future treatments. Some background In advanced melanoma, the cancer often spreads to the brain. This is called brain metastasis. This affects quality of life and also...
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In a nutshell The authors aimed to determine whether hormone drugs abiraterone (Zytiga) and enzalutamide (Xtandi) and chemotherapy drug cabazitaxel (Jevtana) improved overall survival (patients who were still alive after treatment) in prostate cancer patients with advanced, hormone-resistant (castration-resistant) prostate...
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In a nutshell This study investigated whether the levels of certain proteins could be used to predict response to treatment with bevacizumab or chemotherapy in patients with colorectal cancer which has spread beyond the original tumor site. Three proteins were identified as potential biomarkers. Some background In as much as 50% of patients...
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In a nutshell This study investigated which types of immune cells are more active in fighting colorectal cancer which has spread to the liver. It was found that T cells are the most active. Some background It is thought that the immune system response to colorectal cancer (CRC) is an important factor in determining whether the disease progresses...
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In a nutshell This study investigated whether retreatment with cetuximab (Erbitux) was effective in patients whose cancer had progressed after treatment with cetuximab or panitumumab (Vectibix). The results showed that retreatment was effective in patients who had responded to previous treatment. Some background Colorectal cancer progresses...
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