In a nutshell This study examined the benefit of adding chemotherapy to androgen deprivation therapy (ADT) early to treat metastatic hormone-sensitive prostate cancer. Researchers reported a survival benefit when chemotherapy was added to ADT. This benefit was only detected with chemotherapy involving docetaxel (Taxotere). Some background ADT is a...
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In a nutshell This trial aims to test safety and effectiveness of the combined treatment with pembrolizumab (Keytruda) and vemurafenib (Zelboraf) in patients with stage 3 or 4 melanoma. The main outcome to be measured will be the response of the tumors to the treatment. This trial is recruiting in Pittsburgh, Pennsylvania (US). The details Tumors...
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What are the common side effects of advanced prostate cancer treatment, and how can they be managed? An expert panel—including Dr. Jeri Kim, Dr. Sumit Subudhi and Zita Dubauskas Lim—shares an overview of side effects associated with hormonal therapies, chemotherapy and immunotherapy. Published By : Patient Power Date : Aug 18,...
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In a nutshell This study examined predictors of survival for cancer patients with spinal bone metastases. Authors reported that stable and unstable spinal bone metastases had similar survival rates. However, factors predictive of survival were different between groups. Some background When cancer spreads outside of the breast (known as...
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In a nutshell This study examined predictors of survival for cancer patients with spinal bone metastases. Authors reported that stable and unstable spinal bone metastases had similar survival rates. However, factors predictive of survival were different between groups. Some background When cancer spreads outside of the prostate (known as...
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In a nutshell This study examined predictors of survival for cancer patients with spinal bone metastases. Authors reported that stable and unstable spinal bone metastases had similar survival rates. However, factors predictive of survival were different between groups. Some background When cancer spreads outside of the lung (known as...
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In a nutshell This study compared the effectiveness of the chemotherapies FOLFIRI plus bevacizumab (Avastin) and mFOLFOX6 plus bevacizumab in metastatic colorectal cancer. Researchers suggested that these two treatments are equally effective. Some background Roughly 20% of colorectal cancer patients have metastasis (spread to other...
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In a nutshell This phase 2 trial aims to compare the benefit of two types of exercise for men with metastatic castration-resistant prostate cancer. The main outcome to be investigated is the safety of the exercises and its effect on cancer pain. The trial is recruiting in San Francisco (California). The details Metastatic castration-resistant...
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In a nutshell This study aimed to assess whether surgery is beneficial for patients with advanced stage 4 NSCLC that has spread to other parts of the body. The authors concluded that for these patients, surgery resulted in longer survival time compared to those who did not undergo surgery. Some background For many patients with non-small cell lung...
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How does prostate cancer work? With Andrew Schorr as host, Dr. Russell Szmulewitz of the University of Chicago Medical Center gives a short description of the endocrinology of prostate cancer and provides an overview of hormonal therapies. Listen as Dr. Szmulewitz examines the changing treatment paradigm including risks and...
Read MoreIn a nutshell This study compared immediate and delayed androgen deprivation therapy (ADT) for men with relapsed or non-curable prostate cancer. Authors reported improved survival and disease progression with immediate ADT. Some background ADT is a type of hormone therapy used to treat prostate cancer. It targets the production of male hormones...
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In a nutshell This study compared the safety and effectiveness of afatinib (Gilotrif) and erlotinib (Tarceva) as second-line treatments for advanced squamous cell carcinoma (SCC). Authors reported improved survival and disease progression with afatinib compared to erlotinib. Both treatments were associated with a good safety profile. Some background...
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