In a nutshell This study examined the benefit of radiation to limited sites of cancer spread (metastases) in men no longer responding to hormone therapy. Researchers reported effective local cancer control after radiation of lymph node metastases in patients no longer responding to hormone therapy. Some background Hormone therapy is the...
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In a nutshell This study investigated the effects on the immune system associated with the use of ipilimumab (Yervoy) to treat melanoma. Researchers suggested that one-third of the patients treated with ipilimimuab required treatment for the negative side effects. Some background Ipilimumab is an antibody that helps the immune system to...
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In a nutshell This study examined evidence for the benefits of adding chemotherapy early to hormone therapy for metastatic prostate cancer. Authors concluded that early evidence indicates a survival benefit with the addition of chemotherapy for metastatic prostate cancer. Some background Androgen deprivation therapy (ADT) is a type of hormone...
Read MoreIn a nutshell This study examined whether the duration of primary (first round) hormone therapy impacts abiraterone (Zytiga) treatment for metastatic castration-resistant prostate cancer (mCRPC). Researchers concluded that the benefits of abiraterone were not dependent on the duration of primary hormone therapy. Some background Androgen...
Read MoreIn a nutshell The aim of this study was to examine the benefit of adding radiation therapy to androgen deprivation therapy (ADT) for metastatic prostate cancer. Researchers reported a significant survival advantage when radiation therapy was combined with ADT. Some background Metastatic prostate cancer is cancer that has spread from the prostate...
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In a nutshell This trial examined whether bevacizumab (Avastin) is a safe and effective drug for treating patients with advanced NSCLC. The authors concluded that despite varying treatment lengths and dosage, the use of bevacizumab results in an increased overall survival. Some background Bevacizumab is an anti-cancer treatment that blocks the...
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Is chemotherapy a good option for my advanced prostate cancer? APC experts, Dr. Russell Szmulewitz, Dr. Emmanuel Antonarakis, Malecare Director, Joel Nowak, and moderator, Dr. Tomasz Beer, discuss the efficacy of chemotherapy for prostate cancer patients. The panel shares information on quality of life studies and TUPOR...
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In a nutshell This study investigated the benefits of chemotherapy and short-course radiotherapy (SCR) followed by surgery in patients with locally advanced rectal cancer (LARC) with metastasis (spread to other parts of the body). Researchers suggested that this treatment approach is an effective and safe option for LARC patients with operable...
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In a nutshell This study investigated the effect of nivolumab (Opdivo) combined with ipilimumab (Yervoy) in overall survival in the treatment of advanced melanoma. Researchers suggested that this combination is associated with an improved survival when compared to ipilimumab alone. Some background Advanced melanoma is associated with...
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In a nutshell This study summarized updated guidelines for the appropriate treatments for patients with non-small cell lung cancer (NSCLC). Some background Most patients with NSCLC are not diagnosed until the disease is advanced (spread) and survival rates at this late stage of cancer are low. Therefore, it is important that doctors are aware of...
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In a nutshell This study investigated whether paclitaxel (Taxol) alone, or paclitaxel combined with bevacizumab (Avastin), had better outcomes in treating metastatic breast cancer. The authors found that paclitaxel with bevacizumab combination resulted in much better overall survival times (time from treatment until death from any cause)...
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In a nutshell This study investigated the effectiveness of uracil-tegafur and leucovorin (UFT/LV) treatment of liver metastasis (when the cancer spread to the liver) in colorectal cancer patients. Researchers suggested that UFT/LV is an effective and safe option for the treatment of liver metastasis after liver surgery. Some background The...
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