In a nutshell This study wanted to analyse the current literature on using cancer killing viruses as a treatment for melanoma. The study found that there is only one virus that has been approved for use in treatment of melanoma, however there are others being developed, and current results are promising. Some background A new approach to treating...
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In a nutshell This study aimed to investigate the effectiveness of cabazitaxel used for patients with metastatic castration-resistant prostate cancer. This study found that patients treated with cabazitaxel had maintained or improved quality of life and pain control. Some background One treatment option for prostate cancer is androgen deprivation...
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In a nutshell This trial is examining the effectiveness of tesetaxel plus a reduced dose of capecitabine for hormone receptor (HR) positive/HER2 negative advanced breast cancer. The main outcome to be measured will be progression free survival (time from treatment until disease progression). The details Breast cancer is classified into...
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In a nutshell This study aimed to evaluate the use of abiraterone (Zytiga) and olaparib (Lynparza) in advanced prostate cancer. This study concluded that olaparib in combination with abiraterone provided clinical benefit for patients with metastatic castration-resistant prostate cancer compared with abiraterone alone. Some background...
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In a nutshell This trial treated patients with advanced non-small-cell lung cancer with consolidative radiation therapy after chemotherapy. The authors concluded that this treatment plan has potential to improve progression free survival and overall survival in these patients. Some background Initial treatment with...
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In a nutshell This study aimed to look at the safety and effectiveness of fulvestrant (Faslodex) compared to aromatase inhibitors in post-menopausal women with hormone receptor-positive (HR+) breast cancer. The authors found that fulvestrant was a safe and effective treatment in these patients when compared to aromatase inhibitors. Some...
Read MoreIn a nutshell This trial examined the effectiveness of combining the targeted therapy drug pembrolizumab (Keytruda) with chemotherapy at treating certain types of advanced non-small-cell lung cancer. The trial concluded that this combination is more beneficial than chemotherapy alone for treating this subset of patients. Some background PD-1...
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In a nutshell This study examined the survival rates of melanoma patients with brain metastasis treated with new therapies. Researchers concluded that PD-1 agents are associated with improved survival outcomes. Some background More than 50% of melanoma patients develop brain metastasis (cancer spread), with an overall survival of 17 to 22 weeks....
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In a nutshell This study investigated whether the risk of developing melanoma brain metastases (MBM) and survival among patients with MBM has changed since the introduction of more effective therapies. The results found the overall survival for patients with MBM has improved significantly since 2011. Some background In more than 33% of patients...
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In a nutshell This study investigated if sentinel lymph node (SLN) status was linked to Breslow thickness in understanding the prognosis of melanoma (a type of skin cancer). The study concluded that SLN status was not linked to Breslow thickness (BT) for melanoma prognosis. Some background Sentinel lymph nodes...
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In a nutshell This trial aimed to evaluate the use of a second treatment targeting HER-2 in a group of patients that had HER-2, HR positive metastatic breast cancer. This study found that patients treated with dual HER-2 medications with hormone therapy had a superior progression free survival as compared to those using one medication...
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In a nutshell This study examined the effectiveness of the targeted therapy drug nivolumab (Opdivo) at treating advanced non-small-cell lung cancer, particularly for patients with cancer that has spread to the liver. The authors concluded that nivolumab led to an improved overall survival compared to chemotherapy for these patients. Some background...
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