In a nutshell This phase 3 trial is examining the effectiveness and safety of niraparib (Zejula) in combination with abiraterone acetate (Zytiga) and prednisone (Deltasone) vs abiraterone acetate and prednisone plus placebo for patients with metastatic prostate cancer. The main outcome to be measured will be the survival...
Read MoreCurrent stage -Stage IV Posts on Medivizor
Looking for patients with non-small cell lung cancer to test a new immunotherapy combination
In a nutshell This phase 2 trial will investigate the safety and effectiveness of different treatment combinations containing durvalumab (Imfinzi) in non-small cell lung cancer (NSCLC). The main outcome will be the objective response rate (ORR). The details Non-small cell lung cancer (NSCLC) is a common form of lung cancer. It is often diagnosed at...
Read MoreLooking for participants with advanced colorectal cancer to test a new targeted treatment with DS-8201a
In a nutshell This phase 2 trial is examining the effectiveness and safety of DS-8201a in the treatment of advanced HER2 positive colorectal cancer. The main outcome to be measured is the tumor response to the treatment and side effects. The details The standard treatment to advanced colorectal cancers is surgery, chemotherapy and radiation...
Read MoreLooking for participants with stage 2 to 4 rectal cancer to try a new targeted therapy treatment
In a nutshell This phase 2 trial is examining the effectiveness and safety of durvalumab (Imfinzi) in the treatment of advanced rectal cancer that is not prone to genetic abnormalities. The main outcomes to be measured will be tumor response to the treatment and side effects. This trial is being conducted in the US. The details The standard treatment...
Read MoreIs combined treatment with erlotinib and bevacizumab effective in non-small cell lung cancer?
In a nutshell This study investigated the effectiveness of erlotinib (Tarceva) and bevacizumab (Avastin) compared ti erlotinib alone in non-small cell lung cancer (NSCLC). They found that combined treatment improved survival after 12 months. Some background Non-small cell lung cancer (NSCLC) is a common type of lung cancer (LC)....
Read MoreIs pembrolizumab effective as a first-line treatment in lung cancer?
In a nutshell This study investigated the effect of pembrolizumab (Keytruda) in non-small cell lung cancer (NSCLC). They found that this treatment was effective as a first-line therapy for NSCLC. Some background Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. Patients with advanced NSCLC are usually treated...
Read MoreLooking for patients with lung cancer to test a new immunotherapy combination
In a nutshell This phase 1/2 trial is examining the effectiveness of durvalumab (Imfinzi) and monalizumab to treat patients with solid tumors, including lung cancer. The main outcomes to be measured are tumor response to the treatment and side effects. The details Cancer is one of the leading causes of death worldwide. Chemotherapy is only of limited...
Read MoreEvaluating pembrolizumab versus platinum-based chemotherapy for advanced NSCLC
In a nutshell This study evaluated the effectiveness of pembrolizumab (Keytruda) versus platinum-based chemotherapy for patients with non-small cell lung cancer (NSCLC). This study found that pembrolizumab treatment resulted in longer overall survival than treatment with platinum-based chemotherapy. Some background NSCLC is the...
Read MoreOsimertinib compared to standard care for non-small cell lung cancer with EGFR mutations
In a nutshell This study determined whether osimertinib (Tagrisso) was more effective than erlotinib (Tarceva) in patients with non-small cell lung cancer (NSCLC) with the EGFR mutation. The study found that treatment with osimertinib improved survival compared to standard-care treatment for these patients. Some background...
Read MoreLooking for patients with advanced lung cancer to test a new drug
In a nutshell This phase 2 trial will investigate the safety and effectiveness of a new targeted therapy drug, INCMGA00012 in metastatic (spread to other organs) non-small cell lung cancer (NSCLC). The main outcome will be the overall response rate. This trial is recruiting in Texas, United States. The details NSCLC is the most common form of...
Read MoreLooking for participants to test a new treatment combination for advanced colorectal cancer
In a nutshell This trial is examining the effectiveness and safety of treatment with nivolumab (Opdivo) and relatlimab in patients with advanced colorectal cancer. The main outcome to be measured will be tumor response to the treatment. This trial is being conducted in Maryland, US. The details Colorectal cancer is the third most common cancer in the...
Read MoreLooking for men with high-risk prostate cancer features after prostate surgery to trial a type of radiation therapy
In a nutshell This trial is examining the effectiveness of radiation therapy, in treating patients with high-risk prostate cancer features after radical prostatectomy (surgery to remove the prostate gland). The main outcome to be measured will be freedom from failure. Failure is evidence that the cancer has returned. Patients will be followed up for 5...
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