Current stage -Stage IV Posts on Medivizor
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Current stage -Stage IV Posts on Medivizor

Searching for patients with metastatic castration resistant prostate cancer to test a targeted therapy option

Posted by on Jun 24, 2019 in Prostate cancer | 0 comments

In a nutshell This phase 2 trial is examining the effectiveness and safety of trametinib (Mekinist) in patients with metastatic castration-resistant prostate cancer (mCRPC; prostate cancer which has spread from its original place to another area in the body and keeps growing even when the amount of testosterone in the body...

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Searching for patients with prostate cancer to test this new treatment combination

Posted by on Jun 24, 2019 in Prostate cancer | 0 comments

In a nutshell This phase 2 trial is examining the effectiveness and safety of navarixin (MK-7123) in combination with pembrolizumab (Keytruda) in patients with castration-resistant prostate cancer (CRPC; cancer that progresses after hormonal therapy). The main outcome to be measured will be the objective response rate (ORR; tumor shrinkage or...

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Long term outcomes of docetaxel-based chemotherapy with dexamethasone for advanced prostate cancer

Posted by on May 31, 2019 in Prostate cancer | 0 comments

In a nutshell This article investigated the safety and effectiveness of docetaxel (Taxotere)-based chemotherapy in combination with dexamethasone (Decadron) for the treatment of castration-resistant prostate cancer (CRPC). The authors concluded that this treatment combination is a safe and effective treatment option for...

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Searching for patients with metastatic prostate cancer to test this new treatment combination

Posted by on May 28, 2019 in Prostate cancer | 0 comments

In a nutshell This phase 3 trial is examining the effectiveness and safety of niraparib (Zejula) in combination with abiraterone acetate (Zytiga) and prednisone (Deltasone) vs abiraterone acetate and prednisone plus placebo for patients with metastatic prostate cancer. The main outcome to be measured will be the survival...

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Looking for men with high-risk prostate cancer features after prostate surgery to trial a type of radiation therapy

Posted by on Apr 17, 2019 in Prostate cancer | 0 comments

In a nutshell This trial is examining the effectiveness of radiation therapy, in treating patients with high-risk prostate cancer features after radical prostatectomy (surgery to remove the prostate gland). The main outcome to be measured will be freedom from failure. Failure is evidence that the cancer has returned. Patients will be followed up for 5...

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Looking for men with newly diagnosed advanced prostate cancer to test treatment combinations

Posted by on Mar 28, 2019 in Prostate cancer | 0 comments

In a nutshell This trial is examining the effectiveness of radical prostatectomy, in newly diagnosed advanced prostate cancer. The main outcome to be measured will be survival without the cancer worsening. This trial is recruiting in the United States. The details Androgens can cause the growth of prostate cancer cells. Antiandrogen therapy (ADT) may...

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Evaluating a radionuclide treatment for metastatic castration-resistant prostate cancer

Posted by on Mar 26, 2019 in Prostate cancer | 0 comments

In a nutshell This study investigated the effectiveness of a radionuclide (RN), [¹??Lu]-PSMA-617, to treat metastatic castration-resistant prostate cancer (mCRPC) that has worsened after standard treatments. They found that this treatment was safe and effective for these patients. Some background Prostate cancer (PC) affects the...

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Looking for men with prostate cancer, resistant to male hormone suppression, to be treated with medication and radiotherapy

Posted by on Jan 20, 2019 in Prostate cancer | 0 comments

In a nutshell This study evaluates the effectiveness of medication and focal radiation in the treatment of prostate cancer resistant male hormone suppression. The main outcome to be measured in this trial is the number of patients whose cancer does not grow or spread and who are alive at 18 months after treatment. This trial is taking place in Ann...

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Searching for patients with castration resistant metastatic prostate cancer to test cabazitaxel and abiraterone

Posted by on Dec 10, 2018 in Prostate cancer | 0 comments

In a nutshell This trial is examining the safety and effectiveness of cabazitaxel (Jevtana) with abiraterone acetate (Zytiga) compared to abiraterone acetate alone for metastatic (cancer that has spread) castration-resistant prostate cancer (cancer that is no longer responding to hormone therapy). The main outcome measured will be the...

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