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Current stage-Stage IV (Advanced) Posts on Medivizor

Evaluating haploidentical stem cell transplantation for advanced lymphoma

Evaluating haploidentical stem cell transplantation for advanced lymphoma

Posted by on Sep 20, 2020 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This study looked at the effect of a gentler stem cell transplant (SCT) from a partially matched donor for patients with advanced lymphoma. It found that haploidentical SCT is an effective treatment option for these patients. Some background Lymphomas are a group of cancers of white blood cells within the lymph nodes. Common types...

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Evaluating lenalidomide-rituximab treatment for follicular lymphoma

Evaluating lenalidomide-rituximab treatment for follicular lymphoma

Posted by on Aug 23, 2020 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This study looked at the effectiveness of rituxumab (Rituxan) with lenalidomide (Revlimid) for untreated follicular lymphoma (FL). It found that this treatment was more effective than rituxumab with chemotherapy. They also found that blood tests of trace FL can predict outcomes. Some background Follicular lymphoma (FL) is a slow-growing...

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Which is the more effective and safer chemotherapy option for patients with advanced Hodgkin lymphoma?

Which is the more effective and safer chemotherapy option for patients with advanced Hodgkin lymphoma?

Posted by on Jun 7, 2020 in Hodgkin's lymphoma | 0 comments

In a nutshell This study compared the effectiveness and safety of ABVD and BEACOPP chemotherapy for patients with advanced Hodgkin lymphoma (HL). The authors found that while BEACOPP was more effective in the short term, ABVD was as effective in the long term and safer for patients. Some background Chemotherapy is the standard initial treatment...

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Are prognostic scores still useful for predicting outcomes for patients with advanced Hodgkin’s lymphoma?

Posted by on Jan 8, 2020 in Hodgkin's lymphoma | 0 comments

In a nutshell This study examined if international prognostic scores (IPS) could help predict treatment outcomes for patients with advanced Hodgkin's lymphoma (HL). The authors found that the IPS system is losing its predictability as treatment strategies improve for these patients. Some background Patients with HL need to be treated...

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Searching for patients with unresponsive cancer to test a new treatment

Posted by on Jun 29, 2019 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This phase 1/2 trial will investigate the safety of 9-ING-41, for treatment-resistant cancers.  The main outcome will be the number of treatment-related adverse events (TRAEs). This trial is recruiting in the United States. The details Some cancers may not respond to conventional treatment. Treatment-resistant cancers are called...

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Nivolumab plus AVD chemotherapy for patients with advanced classical Hodgkin lymphoma

Posted by on Jun 16, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study assessed the effectiveness of nivolumab (Opdivo) alone or with chemotherapy for patients with advanced classical Hodgkin lymphoma (cHL). This study concluded that nivolumab plus chemotherapy was promising, with manageable side effects for these patients. Some background Standard first-line chemotherapy is highly effective...

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Searching for children with advanced Hodgkin lymphoma to test a new chemoimmunotherapy combination regimen

Posted by on May 24, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study is evaluating the effectiveness of brentuximab vedotin (Adcetris) plus chemotherapy for children with advanced Hodgkin lymphoma (HL). The main outcome to be measured will be the number of patients who respond to treatment. The details Brentuximab vedotin is being tested to treat children who have advanced HL. Brentuximab...

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Evaluating scoring systems used to predict outcomes for patients with advanced HL

Posted by on Apr 24, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study compared the effectiveness of the International Prognostic Scoring System (IPSS) measuring 7 factors (IPSS7) versus the IPSS measuring 3 factors (IPSS3) in predicting outcomes for patients with Hodgkin's lymphoma (HL). This study concluded that there was no significant difference between these scoring systems. Some...

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Evaluating the long-term outcomes of Zevalin for patients with advanced B cell lymphoma

Posted by on Jan 10, 2019 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This study evaluated the long-term outcomes of patients with advanced (stage 3 – 4) non-Hodgkin’s lymphoma (NHL) who received radioimmunotherapy before allogeneic stem cell transplantation (alloSCT). This study concluded that this treatment regimen improved survival in most of these patients. Some background AlloSCT involves...

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Evaluating intensive first-line treatment for patients with advanced Hodgkin’s lymphoma

Posted by on Nov 27, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study evaluated the long-term outcomes of patients with advanced Hodgkin’s lymphoma (HL) who received intensive first-line treatment. This study concluded that intensive first-line treatment with or without radiotherapy led to better long-term outcomes in these patients. Some background For patients with advanced HL,...

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Long-term outcomes of radioimmunotherapy in patients with follicular lymphoma

Posted by on Oct 5, 2018 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This study investigated the long-term outcomes of radioimmunotherapy following first-line (primary) R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone) in previously untreated patients with advanced-stage follicular lymphoma (FL). This study concluded that this treatment approach is effective and well-tolerated in...

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