In a nutshell This study compared the ability of two drugs, ganitumab and conatumumab, to treat patients with metastatic colorectal cancer when added to chemotherapy. Some background Cancer cells express various structures on their surface (called receptors) that may stimulate growth and help avoid destruction by the immune system. Drugs that...
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The effect of cetuximab with chemotherapy in patients with unresectable liver metastases
In a nutshell This study explored whether cetuximab (erbitux) can benefit patients with unresectable colorectal liver metastases. The ability to perform surgery to remove part or all of the tumor growth in the liver (the resection rate) was compared between patients receiving cetuximab in combination with chemotherapy, to those receiving chemotherapy...
Read MoreSurgical removal of metastatic stage IV melanomas can increase length of survival and overall survival rates
In a nutshell This article provides the results of a study investigating surgical removal of metastatic stage IV melanomas. Results showed that surgical removal of metastatic melanomas can provide an increased survival time compared to systemic treatment alone. Some background Cutaneous melanoma which spread to other organs of the body (stage IV)...
Read MoreRegorafenib is a new drug for the treatment of metastatic colorectal cancer after failure of previous therapies
In a nutshell The present study evaluated the efficacy of a new drug, Regorafenib, for the treatment of refractory (progressing despite several lines of treatment) metastatic colorectal cancer (mCRC). Some background Many of the patients with colorectal cancer do not present any symptoms in the early stages of the disease so the cancer...
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