In a nutshell This phase 1/2 trial will investigate the safety of 9-ING-41, for treatment-resistant cancers. The main outcome will be the number of treatment-related adverse events (TRAEs). This trial is recruiting in the United States. The details Some cancers may not respond to conventional treatment. Treatment-resistant cancers are called...
Read MoreCurrent stage-Stage IV Posts on Medivizor
Searching for patients with unresponsive cancer to test a new treatment
In a nutshell This phase 1/2 trial will investigate the safety of 9-ING-41, for treatment-resistant cancers. The main outcome will be the number of treatment-related adverse events (TRAEs). This trial is recruiting in the United States. The details Some cancers may not respond to conventional treatment. Treatment-resistant cancers are called...
Read MoreLooking patients with metastatic triple negative breast cancer to trial a radiation treatment
In a nutshell This phase 2 trial will investigate the effectiveness of stereotactic body radiotherapy (SBRT) in patients with metastatic cancer. The main outcome will be progression-free survival (PFS; survival without the cancer getting worse). This trial is recruiting in multiple locations in New York and New Jersey, US. The details...
Read MoreLooking patient with advanced melanoma to test a new drug
In a nutshell This phase 1 study will investigate the dose range and effectiveness of an experimental drug, XmAb23104, in the treatment of advanced melanoma and other solid tumors. The main outcome will be the safety and tolerability of XmAb23104. This trial is recruiting in Georgia, Texas, and Virginia, the United States. The details...
Read MoreLong-term outcomes for dabrafenib plus trametinib treatment for metastatic melanoma.
In a nutshell This study wanted to find out how well patients with advanced melanoma with mutations (abnormal genes) survive when treated with dabrafenib (Tafinlar) and trametinib (Mekinist) combination. The study found that long term, patients survived moderately well with this treatment. Some background Advanced melanoma can be hard to treat. In...
Read MoreSearching for patients with melanoma to test this new melanoma vaccine with or without immunotherapy
In a nutshell This trial is examining the effectiveness and safety of 6MPH, a melanoma vaccine with adjuvants and a CDX-1127 monoclonal antibody in patients with melanoma. The main outcomes to be measured will be side effects and the response of the immune system. This trial is recruiting in Virginia, United States. The details A treatment option...
Read MoreSearching for patients with advanced triple negative breast cancer to test this new treatment option
In a nutshell This phase 1/2 trial is examining the effectiveness and safety of KY1044 alone and in combination with atezolizumab (Tecentriq) for patients with advanced cancers who are not suitable for any other treatment or have failed all other treatment options. The main outcomes to be measured will be the occurrence and severity of side effects and...
Read MoreSearching for patients with advanced non-small cell lung cancer to test a new T-cell treatment
In a nutshell This phase 2 trial will investigate the effectiveness of genetically-engineered cell treatment (GECT) in advanced cancer. The main outcome will be the response to treatment. This trial is recruiting at the National Cancer Institute, Maryland, US. The details There are limited treatment options for advanced cancer. One...
Read MoreSearching for patients with advanced colorectal cancer to test a new T-cell treatment
In a nutshell This phase 2 trial will investigate the effectiveness of genetically-engineered cell treatment (GECT) in advanced cancer. The main outcome will be the response to treatment. This trial is recruiting at the National Cancer Institute, Maryland, US. The details There are limited treatment options for advanced cancer. One...
Read MoreSearching for patients with small-cell lung cancer or neuroendocrine tumors to trial a new treatment regime
In a nutshell This trial aims to find out how well nivolumab (Opdivo) and temozolomide (Temodal) work in treating small-cell lung cancer that has come back, is resistant to treatment or has spread through the body. The main outcome that will be measured is how well the patients respond to the treatment. The study is taking place in the United...
Read MoreSearching for patients with advanced melanoma to trial a new treatment combination
In a nutshell This trial aims to look at how safe and effective a new combination of lenvatinib (Lenvima) and pembrolizumab (Keytruda). The main outcome measured will be the number of patients who respond to treatment, and to what extent they respond. This study is being conducted in Spain, Sweden, and the United States. The details...
Read MoreSearching for patients with HER2 positive breast cancer that has spread to trial a new treatment
In a nutshell This trial aims to see if combining two medications, T-DM1 (Kadcycla) and palbociclib (Ibrance) is better than just using T-DM1 in treating HER2+ breast cancer that has spread. The main outcome that will be measured is survival without the cancer growing or spreading. The study is being conducted in Arizona, the United States. The...
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