In a nutshell This study wanted to find out which of three medicines was best for treating breast cancer, palbociclib (Ibrance), ribociclib (Kisquali), or abemaciclib (Verzenio). The study found that the medications all worked equally as well, but there were different side effects for each one. Some background Estrogen receptor positive (ER+) breast...
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In a nutshell This study investigated long term rectal cancer outcomes in patients who received chemotherapy, radiation therapy, and transanal microsurgery. Researchers suggested that this treatment improves treatment outcomes and quality of life of patients. Some background The standard treatment for rectal cancer is surgery. However,...
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In a nutshell This article investigated the long-term safety and effectiveness of autologous breast reconstruction (ABR; uses tissue from another place on your body to form a breast shape) on women after breast removal for invasive breast cancer. The authors concluded that this treatment is safe and had no effect on relapse...
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In a nutshell This trial evaluates a specific type of radiation therapy for advanced prostate cancer. The main outcome to be measured is whether or not the therapy will damage the surrounding organs. This trial is taking place in Pennsylvania, USA. The details Prostate cancer is an uncontrolled growth of the cells which make up the...
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In a nutshell This study investigated the effectiveness of chemotherapy and radiation therapy (CRT) with capecitabine (Xeloda) before surgery in elderly patients with locally advanced rectal cancer. Researchers suggested that this treatment is safe and well tolerated in the elderly. Some background Colorectal cancer is the third most commonly...
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In a nutshell This study wanted to find out if joint pain is associated with falling down in patients with breast cancer who were treated with aromatase inhibitors. The study found that the patients who reported having joint pain were more likely to have a fall than those who had no joint pain. Some background Aromatase inhibitors are medications...
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In a nutshell This study wanted to find out if treating breast cancer with everolimus (Afintor) and endocrine therapy is better than only treating with endocrine therapy. The study found that using everolimus in addition to endocrine therapy had a significant benefit to survival in these patients. Some background Breast cancer is classified into types...
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In a nutshell This study wanted to find out if ixabepilone (Ixempra) and capecitabine (Xeloda) work for treating triple-negative breast cancer in patients with hard to treat disease compared to using capecitabine alone. The study found that adding ixabepilone to treatment resulted in longer survival without the cancer progressing. Some background...
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In a nutshell This study wanted to find out if using the medication erlotinib (Tarceva) in patients with non-small cell lung cancer improved survival. The study found that using erlotinib was safe, and may reduce the need for radical surgery in patients with non-small cell lung cancer. Some background Epidermal growth factor receptor (EGFR) is...
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In a nutshell This study investigated the effect of apalutamide (Erleada) on health-related quality of life (H-QoL) in patients with prostate cancer. This study found that apalutimide preserved H-QoL while prolonging time taken for cancer to spread. Some background One treatment option for patients with prostate cancer is androgen...
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In a nutshell This study compared two different types of radiation therapy after prostate surgery for prostate cancer, hypofractionated postprostatectomy radiation therapy (hypoPORT) and conventional postprostatectomy radiation therapy (coPORT). Results showed that hypoPORT may be effective in prostate cancer control and with similar side effects as...
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In a nutshell This study wanted to find out how well two chemotherapy drugs, fotemustine (Muphoran) and temozolomide (Temodar) work in treating melanoma that had spread to other organs (metastatic melanoma). The study found that some of the patients responded to this combination of medications. Some background Metastatic melanoma can often be...
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