In a nutshell This article reviewed treatment options for patients with high-risk prostate cancer. Some background Prostate cancer is a cancer that starts in the prostate gland. There are different types of treatment for patients with prostate cancer. Treatment choice depends on disease stage or whether the cancer has spread to other parts of the...
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In a nutshell This study investigated whether tummy infections (TIs) after surgery are associated with colorectal cancer outcomes. Researchers suggested that TIs might be associated with a shorter time until recurrence. Some background Colorectal cancer is a common cancer in the US affecting more than 145,000 people every year. Surgery is...
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In a nutshell This study wanted to find out what the best order is for treating melanoma with immunotherapy medications and surgery. The study found that immunotherapy before surgery resulted in better survival outcomes for these patients. Some background Treatments for melanoma have changed in the last few years. A newer treatment is...
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In a nutshell This study examined the safety and effectiveness of osimertinib (Tagrisso) compared to other targeted therapies for advanced non-small cell lung cancer (NSCLC). The authors concluded that osimertinib improved patient survival. Some background NSCLC accounts for the majority of lung cancers. Some...
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In a nutshell This study evaluated the patient-reported outcomes after treatment with durvalumab (Imfinzi) for stage III non-small-cell lung cancer (NSCLC) that cannot be surgically removed. This study concluded that durvalumab did not affect the quality of life of these patients. Some background NSCLC is the most common form of lung cancer...
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In a nutshell This study investigated the effects of complete mesocolic excision (CME) in patients with right-side colon cancer. Researchers suggested that CME reduces the risk of recurrences (when cancer comes back) in these patients. Some background Colorectal cancer is one of the most common cancers worldwide. The standard treatment is surgery and...
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In a nutshell This study investigated the effectiveness of radiation therapy (RT) after surgery in patients with T4 (cancer that has grown outside of the colon outer layer and invades the surrounding tissues) colon cancer. Researchers suggested that RT improved overall survival in these patients. Some background Colorectal cancer is the third...
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In a nutshell This study wanted to find out how well patients with advanced melanoma treated with certain medications survived outside of clinical trials. The study found that patients treated with nivolumab (Opdivo) and ipilimumab (Yervoy) or patients treated with anti-PD1 antibodies had longer survival compared to those treated with BRAF/MEK...
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In a nutshell This study investigated the effect of chemotherapy on the survival of patients with stage 2 and 3 mucinous colorectal cancer (mucCRC). Researchers suggested that chemotherapy improved the survival of these patients. Some background Colorectal cancer is the third most common cancer in the US in 2019. Up to 20% of colon cancer is mucCRC....
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In a nutshell This article reviewed treatment options for patients with advanced melanoma. Some background Treatment for melanoma depends on several factors, including the disease stage. Advanced melanoma is diagnosed when cancer can be detected outside of the original tumor. This makes treatment difficult. Currently, there...
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In a nutshell This trial is examining the safety and effectiveness of experimental drug mRNA-2752 in patients with advanced triple-negative breast cancer. The main outcome of the trial will be the number of side effects experienced by patients and response to treatment. This trial is recruiting in the United States and Israel. The details...
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In a nutshell This study compared nivolumab (Opdivo) plus ipilimumab (Yervoy) to either drug alone for the treatment of advanced melanoma. The authors concluded that nivolumab plus ipilimumab or nivolumab alone increased survival compared to ipilimumab alone for these patients. Some background Advanced melanoma is a type of skin cancer that...
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