In a nutshell This study examined the effect of aspirin on prostate cancer mortality. Some background Multiple studies have suggested that prostate cancer patients could benefit from regular aspirin use. Aspirin is a salicylate that works to reduce substances in the body that cause pain, fever and inflammation. It is thought that aspirin...
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In a nutshell This review explored the benefits of radiation therapy in the management of breast cancer. Some background Radiation therapy plays an important role in the treatment of breast cancer. Radiation therapy has been shown to decrease the risk of cancer recurrence after surgery and improve survival rates among invasive cancer patients....
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In a nutshell This study examined the safety and efficacy of gefitinib (Iressa) in EGFR-positive, non-small-cell lung cancer among Caucasian patients. Some background Many types of cancer, including non-small-cell lung cancer, are caused by genetic mutations. A mutation in the epidermal growth factor receptor (EGFR) gene leads to the...
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In a nutshell This study investigated the efficacy and safety of EZN-2208, an anti-cancer agent, in patients with advanced colorectal cancer. Some background Colorectal cancer is cancer in the colon and rectum that has high tendency to metastasize (spread into distant organs) or to spread locally. Cancer results from uncontrolled...
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In a nutshell This study examined overall survival rates following treatment with different dosages of fulvestrant (Faslodex) in patients with recurrent or metastatic estrogen receptor-positive breast cancer. Some background Estrogen receptor-positive (ER+) breast cancers are dependent on the hormone estrogen for continued growth and spread....
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In a nutshell This study evaluated breast cancer risk and outcomes among postmenopausal women using hormone replacement therapy. Some background Progesterone and estrogen are steroid hormones that have a crucial role in female maturation and reproduction processes. The female menstrual cycle, ovulation and pregnancy are only part of the...
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In a nutshell This trial compared the effects of different support groups for distressed breast cancer patients. Some background Cancer diagnosis and treatments are known to be a major cause of depression and distress. Among breast cancer survivors, the risk of tumor recurrence and frequent screening contribute to patient stress and depression...
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In a nutshell This study examined whether biomarkers were predictive of recurrence (return of the cancer) and overall survival rates in patients with lung cancer. Some background Treatment for stage 2 or 3 lung cancer generally includes the surgical removal (resection) of the tumor, followed by additional (adjuvant) therapies such as chemotherapy...
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In a nutshell This study examined the use of electrochemotherapy in patients with skin (cutaneous) metastases from melanoma. Some background Melanoma recurs (comes back) in 80% of patients within 5 years, often at sites distant to the original tumor. Melanoma cells can be spread through both the bloodstream and the lymphatic system, and it often...
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In a nutshell This early phase study assessed the efficacy and safety of a new drug, Orteronel (TAK-700), in patients with castration-resistant prostate cancer. Some background Androgen deprivation therapy (ADT), or castration therapy, is the standard of care for advanced prostate cancer. ADT usually involves either surgical...
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In a nutshell The current study examined whether the proteins versican and lumican were predictive of prognosis among colon cancer patients. Some background Colon cancer treatments vary depending on the type and stage of the disease. Patients with advanced cancer, which has invaded the surrounding lymph nodes, usually receive chemotherapy along...
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In a nutshell This study examined whether the timing of adjuvant chemotherapy affects survival among women with breast cancer. Some background Surgical resection to remove all cancerous tissue is the standard of care for the treatment of breast cancer. After surgery, many patients also undergo adjuvant treatments (additional therapy following...
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