In a nutshell The authors aimed to determine patient and cancer outcome following treatment with pelvic lymph node dissection and robot-assisted prostate surgery. Some background In some prostate cancer patients tumors can spread into the lymph nodes (sites that hold cells used to fight infection). A pelvic lymph node dissection is used to...
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In a nutshell This study investigated the effects of hormone therapy given before brachytherapy (a form of radiation therapy) on the survival of prostate cancer patients with at least one risk factor for coronary artery disease compared to those with no risk factors. Some background Quite often, hormone therapy such as anti-androgen therapy...
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In a nutshell This paper studied the occurrence of bone marrow neoplasms after adjuvant breast cancer therapy. Some background Adjuvant therapy (treatment given after initial cancer therapy) has helped to improve survival of patients with early stage breast cancer. However, there are still some short and long term complications that can...
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In a nutshell The authors aimed to determine patient outcomes using the standard classification systems in uveal melanoma patients. Some background Uveal melanoma is a rare form of cancer that occurs in the eye. The TNM classification system can be used to determine the extent of melanoma present and can help identify the most effective...
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In a nutshell This paper studied whether a mindfulness meditation program could reduce stress and depression in young breast cancer survivors. Some background Studies have shown that younger women are more stressed and depressed compared to older women after being diagnosed with cancer. They are also more likely to be fatigued and have sleep...
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In a nutshell The authors reviewed the effect of androgen deprivation therapy in treating patients with advanced prostate cancer. Some background Androgen deprivation therapy (ADT) is a form of hormone treatment that targets the male sex hormones involved in prostate cancer, such as testosterone. ADT is the standard treatment for cancer that has...
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In a nutshell The authors aimed to determine patients who were at risk of cancer returning after surgery for prostate cancer. Some background Radical prostatectomy involves surgically removing the prostate from patients that have prostate cancer. It is used as a treatment option in early stage prostate cancer where the tumor has not spread outside...
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In a nutshell The authors aimed to determine factors that predicted survival after return of non-small cell lung cancer. Some background Non-small cell lung cancer (NSCLC) is the most common form of lung cancer. In cases of cancer recurrence (return), NSCLC can reoccur at different sites in the body from the primary site or can be limited to a...
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In a nutshell This review highlights the existing concerns facing treatment of locally advanced rectal cancer patients with preoperative chemotherapy. Some background Locally advanced rectal cancer indicates that the cancer has spread beyond the lining of the rectum or has spread to the nearby lymph nodes. Preoperative chemoradiotherapy (PCRT;...
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In a nutshell The aim of this trial will be to determine whether participating in a physical activity program, along with health education, is more effective at decreasing colorectal cancer recurrence than health education alone. The primary outcome measured in this trial will be disease-free survival (how long following treatment a patient remains...
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In a nutshell This study compared two treatment options for patients with epidermal growth factor receptor (EGFR) mutation-positive metastatic non-small cell lung cancer (non-small-cell lung cancer that has an abnormal EGFR gene and has spread to distant sites). Some background One possible cause of non-small cell lung cancer is a mutation in the...
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In a nutshell This paper evaluated early discontinuation of trastuzumab (Herceptin) therapy and how cardiovascular events (disease associated with the heart and blood vessels) associated with this affect survival in older women with breast cancer. Some background Human epidermal growth factor receptor 2 (HER2) is a protein that can be found...
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