In a nutshell This study investigated the long-term effectiveness bevacizumab (Avastin) with chemotherapy for HER2-negative locally recurrent/metastatic breast cancer. This study concluded that while bevacizumab combined with chemotherapy significantly improved time to disease progression compared with chemotherapy alone in the first two phases...
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In a nutshell This study examined the benefit of radiation to limited sites of cancer spread (metastases) in men no longer responding to hormone therapy. Researchers reported effective local cancer control after radiation of lymph node metastases in patients no longer responding to hormone therapy. Some background Hormone therapy is the...
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In a nutshell This study examined evidence for the role of prostate surgery in treating high-risk prostate cancer. Authors concluded that surgery is an effective primary treatment option for men with high-risk disease. Some background Localized prostate cancer is cancer that is confined to the prostate gland. Men with high-risk localized prostate...
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In a nutshell This study examined whether immunotherapy with sipuleucel-T (Provenge) shows a greater immune response if administered before or after androgen deprivation therapy (ADT). Authors present preliminary evidence of improved immune cell response when sipuleucel-T was administered first in patients with recurrent prostate cancer at high risk of...
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Transcript Please remember the opinions expressed on Patient Power are not necessarily the views of our sponsors, contributors, partners or Patient Power. Our discussions are not a substitute for seeking medical advice or care from your own doctor. That’s how you’ll get care that’s most appropriate for you. Janet...
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In a nutshell This study examined the benefit of administering chemotherapy before prostate surgery in men with intermediate- to high-risk prostate cancer. Researchers reported preliminary evidence of a cancer-specific survival benefit when chemotherapy was administered before surgery. Some background Prostate surgery is a first-line treatment for...
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In a nutshell This study investigated the benefits of pre-surgery chemotherapy and radiation therapy (CRT) in patients with rectal cancer and pelvic lymph node metastasis (spread of cancer). Researchers suggested that CRT may have a beneficial impact in the disease outcomes of these patients. Some background CRT followed by surgery is the...
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Are there any immunotherapy approaches currently available to advanced prostate cancer patients? Patient Power Founder and Host, Andrew Schorr, leads a discussion with prostate cancer experts Dr. William Catalona of Lurie Cancer Center and Dr. Russell Szmulewitz on immunotherapy research. Dr. Szmulewitz gives a short account of immunology...
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In a nutshell This study investigated the predictive factors for the outcomes of stage 3b melanoma. Researchers suggested that patients older than 50 years old, with tumors thicker than 2 mm and positive pelvic lymph nodes are more at risk of death by stage 3b melanoma. Some background The incidence of melanoma has been rising worldwide....
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In a nutshell This study compared the effectiveness of different treatment options available for localized prostate cancer. Authors reported low rates of prostate cancer-specific mortality across all treatment groups. However, surgery and radiation therapy were associated with a lower rate of disease progression and metastases compared to active...
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In a nutshell This study investigated the effect of granulocyte-macrophage colony-stimulating factor (GM-CSF) and peptide vaccination (PV) on survival of patients with advanced melanoma. Researchers suggested that neither GM-CSF nor PV were associated with improved survival. Some background GM-CSF stimulates the immune system to produce more...
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In a nutshell The authors compared the effectiveness of different chemotherapy agents in combination with radiation. They stated that a combination of etoposide (Etopophos) and cisplatin (Platinol) was more effective then docetaxel (Taxotere) and cisplatin when combined with radiation therapy. Some background...
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