In a nutshell This study aimed to investigate the benefits of fulvestrant (Faslodex) treatment in advanced breast cancer patients. This study concluded that fulvestrant provides a benefit in patients with advanced breast cancer who have visceral metastasis. Some background Advanced breast cancer (ABC) has spread to the lymph nodes and...
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In a nutshell This study aimed to compare the effectiveness of the combination of fulvestrant (Faslodex) and abemaciclib to fulvestrant alone in patients with advanced breast cancer. This study concluded that the combination of fulvestrant and abemaciclib had improved outcomes for patients when compared to fulvestrant alone. Some background...
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In a nutshell This study aimed to investigate the association between beta blocker use and outcomes in HER2 negative breast cancer (BC) patients. This study concluded that beta blocker use leads to improved progression free survival in BC patients. Some background Beta blockers are therapies used to treat various heart related conditions....
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In a nutshell This study reviewed the effectiveness and safety of combined treatment with BRAF and MEK inhibitors in patients with advanced melanoma. Researchers suggested that combined treatment of BRAF and MEK inhibitors was associated with better responses than other treatments. Some background Some melanoma patients have a mutation...
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In a nutshell This study investigated the effect of coffee intake in stage 3 colon cancer. Researchers suggested that an increased coffee intake is associated with a lower risk of cancer recurrence (when the cancer comes back) and improved survival. Some background High levels of insulin in the blood, inactive lifestyle, obesity and diet with high...
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In a nutshell This study compared the side effects and outcome of two drug regimens in women with high-risk node-positive breast cancer (BC). Both treatment regimens were found to have similar survival outcomes. Some background Standard treatment in node positive BC (cancer that has spread to the lymph nodes) consists of two categories of...
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In a nutshell This study investigated whether metronomic chemotherapy with oral vinorelbine (Navelbine) and capecitabine (Xeloda) was effective in treating patients with advanced HER2-negative breast cancer (BC). This form of treatment was found to be safe and effective for this patients group. Some background Metronomic chemotherapy is a form of...
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In a nutshell This study investigated whether exercise was associated with a reduction in the risk of cardiovascular disease (CVD) in patients with non-metastatic breast cancer (BC). Exercise was found to be linked to a significant reduction in the risk of CVD for this patient group. Some background CVD is a leading cause of death among women with...
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In a nutshell This study investigated whether chemotherapy after rectal surgery improves survival of rectal cancer patients. Researchers suggested that chemotherapy after rectal surgery is associated with improved survival. Some background Rectal cancer affects almost 40,000 people annually in the United States. Roughly 50% of these patients...
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In a nutshell The authors aimed to determine guidelines for the treatment of relapsing, metastatic, and hormone-resistant prostate cancer. Some background Metastatic prostate cancer (advanced cancer) is cancer that has spread outside of the prostate to other organs of the body, despite treatment. Hormone therapy is the standard...
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In a nutshell This study investigated whether a high proportion of dense breast tissue is associated with an increased risk of developing contralateral breast cancer (CBC, cancer in the other breast). This study determined that those with dense breasts at the time of original diagnosis were significantly more likely to develop CBC than those...
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In a nutshell The aim of this study was to determine whether radiation therapy in combination with hormonal therapy improved survival in men with prostate cancer that has spread to the lymph nodes after surgery. Researchers concluded that patients treated with radiation therapy and hormone therapy had a significantly higher survival rate compared to...
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