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Current stage -Stage III Posts on Medivizor

Comparing the safety and effectiveness of hormonal therapy alone versus chemo-hormonal therapy before prostate surgery in men with locally advanced prostate cancer

Comparing the safety and effectiveness of hormonal therapy alone versus chemo-hormonal therapy before prostate surgery in men with locally advanced prostate cancer

Posted by on Oct 13, 2024 in Prostate cancer | 0 comments

In a nutshell This study investigated whether adding docetaxel (Taxotere) chemotherapy to standard hormonal therapy (HT) before radical prostatectomy (RP – prostate-removal surgery) improved the survival of men with locally advanced prostate cancer (PCa) compared to hormonal therapy alone. It concluded that the addition of...

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Evaluating the long-term effectiveness and safety of adding abiraterone acetate and prednisolone with or without enzalutamide in patients with metastatic prostate cancer starting androgen-deprivation therapy.

Evaluating the long-term effectiveness and safety of adding abiraterone acetate and prednisolone with or without enzalutamide in patients with metastatic prostate cancer starting androgen-deprivation therapy.

Posted by on May 26, 2024 in Prostate cancer | 0 comments

In a nutshell The study evaluated the long-term effectiveness and safety outcomes of adding abiraterone acetate (AA; Zytiga) and prednisolone (P; Deltasone) with or without enzalutamide (Xtandi) in patients with metastatic prostate cancer (PC) starting androgen-deprivation therapy (ADT). The data showed that enzalutamide and AA+P should not be combined...

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Looking patients with advanced cancer to test a new immunotherapy combination

Posted by on May 31, 2019 in Prostate cancer | 0 comments

In a nutshell This phase 1/2 trial will investigate BMS-986253, an experimental drug, in combination with nivolumab (Opdivo) to treat advanced cancer. The main outcomes will be the occurrence of side effects and tumor response. The details Advanced cancers have limited treatment options. New drugs are in development to improve patient prognosis. These...

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Searching for patients with stage 3-4 prostate cancer to test a treatment combination. 

Posted by on Mar 28, 2019 in Prostate cancer | 0 comments

In a nutshell This trial is examining the effectiveness of radiation therapy with or without apalutamide (Erleada) in the treatment of stage 3-4 prostate cancer. The main outcome to be measured will be survival without cancer worsening. This trial is recruiting in Canada and the United States. The details Radiation therapy uses high energy x-ray...

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Comparing daily versus weekly imaging checks in radiation therapy for prostate cancer

Posted by on Aug 26, 2018 in Prostate cancer | 0 comments

In a nutshell This study aimed to investigate the best timing of treatment verification imaging used in radiation therapy for patients with prostate cancer. This study found that patients undergoing daily imaging had less risk of their cancer returning and had reduced rectal side-effects. Some background One main treatment option for prostate cancer...

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Searching for patients to test the effectiveness of docetaxel and carboplatin in the treatment of advanced prostate cancer

Posted by on Jun 6, 2017 in Prostate cancer | 0 comments

In a nutshell The aim of this trial is to determine the effectiveness of a combination of the chemotherapies docetaxel (Taxotere) and carboplatin (Paraplatin) in advanced (spread beyond the prostate) prostate cancer. The main outcome to be measured is the number of patients who experience a decrease of 50% in prostate specific...

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Survival benefit when adding radiation therapy to hormone therapy for metastatic prostate cancer

Posted by on Nov 7, 2016 in Prostate cancer | 0 comments

In a nutshell The aim of this study was to examine the benefit of adding radiation therapy to androgen deprivation therapy (ADT) for metastatic prostate cancer. Researchers reported a significant survival advantage when radiation therapy was combined with ADT. Some background Metastatic prostate cancer is cancer that has spread from the prostate...

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The effect of different radiation therapy schedules on erectile function

Posted by on Oct 9, 2016 in Prostate cancer | 1 comment

In a nutshell This study compared the side effects of external beam radiation therapy (EBRT) and hypofractioned EBRT (H-EBRT) on erectile and sexual function. Researchers reported similar effects of EBRT and H-EBRT on erectile and sexual function up to 3 years after treatment. Some background Radiation therapy is a common treatment for localized...

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LDH as an early predictor of cancer survival

Posted by on Feb 8, 2016 in Prostate cancer | 1 comment

In a nutshell This study investigated the relationship between lactate dehydrogenase (LDH) levels and cancer-specific survival. Researchers concluded that LDH can be used as an early indicator of cancer outcomes. Some background Early cancer detection methods have significantly improved cancer survival rates. There is increasing evidence to...

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