Current stage-Stage III Posts on Medivizor
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Current stage-Stage III Posts on Medivizor

Trastuzumab emtansine plus pertuzumab in patients with HER2-positive breast cancer

Posted by on Jul 14, 2019 in Breast cancer | 0 comments

In a nutshell This study wanted to find out which treatment was better before surgery for patients with HER2-positive breast cancer, trastuzumab emtansine (Kadcycla) plus pertuzumab (Perjeta), or a standard treatment. The study found that patients treated with trastuzumab emtansine plus pertuzumab (TEP) were more likely to have cancer...

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Looking for patients with locally advanced rectal cancer to test a chemotherapy treatment

Posted by on Jun 29, 2019 in Colorectal cancer | 0 comments

In a nutshell This phase 2 trial is examining the effectiveness of FOLFOX chemotherapy to treat patients with rectal cancer, without surgery and radiation. The main outcome to be measured will be the tumor response to the treatment. This study is being conducted in New York, US. The details This year an estimated 44,180 people will be diagnosed with...

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Searching for patients with advanced triple negative breast cancer to trial a new treatment into the tumor

Posted by on Jun 28, 2019 in Breast cancer | 0 comments

In a nutshell This phase 2 study will investigate Tavokinogene Telseplasmid Electroporation (TTE) in combination with pembrolizumab (Keytruda) in advanced or not suitable for surgery triple-negative breast cancer (TNBC). The main outcome will be the objective response rate (ORR). This trial is recruiting in the United States and...

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Searching for patients with colorectal cancer to test this new treatment combination

Posted by on Jun 24, 2019 in Colorectal cancer | 0 comments

In a nutshell This phase 2 trial is examining the effectiveness and safety of navarixin (MK-7123) in combination with pembrolizumab (Keytruda) in patients with colorectal cancer (CRC). The main outcome to be measured will be the objective response rate (ORR; tumor shrinkage or disappearance).  The details A treatment option for patients with...

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Searching for patients with lung cancer that cannot be operated on to test durvalumab after chemotherapy and radiation

Posted by on Jun 24, 2019 in Lung cancer | 0 comments

In a nutshell This phase 2 trial will investigate the safety and effectiveness of durvalumab (Imfinzi) in patients with stage III non-small cell lung cancer (NSCLC).  The main outcomes will be the number of treatment-related adverse events (TRAEs) and progression-free survival (PFS).  The details Non-small cell lung cancer (NSCLC)...

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Long-term outcomes for dabrafenib plus trametinib treatment for metastatic melanoma.

Posted by on Jun 23, 2019 in Melanoma | 0 comments

In a nutshell This study wanted to find out how well patients with advanced melanoma with mutations (abnormal genes) survive when treated with dabrafenib (Tafinlar) and trametinib (Mekinist) combination. The study found that long term, patients survived moderately well with this treatment. Some background Advanced melanoma can be hard to treat. In...

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Looking patients with advanced cancer to test a new immunotherapy combination

Posted by on May 31, 2019 in Breast cancer | 0 comments

In a nutshell This phase 1/2 trial will investigate BMS-986253, an experimental drug, in combination with nivolumab (Opdivo) to treat advanced cancer. The main outcomes will be the occurrence of side effects and tumor response. The details Advanced cancers have limited treatment options. New drugs are in development to improve patient prognosis. These...

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