In a nutshell This study assessed the safety and efficacy of stereotactic body radiation therapy (SBRT) in patients with localized prostate cancer treated with CyberKnife (CK). Some background SBRT is a minimally invasive radiation therapy technique that delivers beams of high dose radiation to the cancer with extreme accuracy. Therefore, there is...
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In a nutshell This present study evaluated the role of menopausal symptoms in the prognosis of breast cancer patients. Some background Menopause is the period in a woman’s life after menstruation stops and the ovaries become inactive, defined as 12 months after a woman's last period. With menopause, the level of female sex hormones such...
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In a nutshell This study evaluated whether the number of resected lymph nodes is associated with survival rate in patients with Non-Small Cell Lung Cancer (NSCLC). Some background Lung cancer cells can reach the lymph nodes (small collections of immune cells) around the bronchi (the airway ducts that deliver air to the lungs) and in the area...
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In a nutshell The study evaluated whether active surveillance (AS) is a safe approach and can prevent over-treatment in patients with prostate cancer. Some background In the recent years, survival rates for prostate cancer patients have increased due to more advanced screening methods, which allow for early detection and prevention of...
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In a nutshell This study evaluated the outcomes of prostate cancer patients with persistently detectable levels of prostate-specific antigen (PSA) following radical prostatectomy (RP). Some background Radical prostatectomy or RP (surgical removal of the prostate gland and some tissue around it) is a common treatment for patients with prostate...
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In a nutshell This study investigated whether a Mediterranean diet is linked to better outcomes in men diagnosed with prostate cancer. Some background Dietary changes are thought to affect the development and progression of prostate cancer. However, no study to date has reached conclusive results regarding the effects of diet on mortality from...
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In a nutshell This study evaluated the use, effects and adherence of trastuzumab (herceptin) as treatment for patients with breast cancer. Some background Trastuzumab is often prescribed as adjuvant (additional) therapy for human epidermal growth factor receptor-2 positive (HER2+) breast cancer. HER2 is a protein found on the surface of some...
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In a nutshell This study investigated the effect of lateral pelvic lymph node dissection on survival of rectal cancer patients. Some background Removal of the lymph nodes in the area surrounding lower rectal cancer (lateral pelvic lymph node dissection or LPND) is often performed during surgery to remove the cancer. LPND is usually performed if...
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In a nutshell This phase II clinical trial examined the safety and efficacy of adding a drug called rh-endostatin (Endostar) to chemotherapy in breast cancer patients. Some background Cancer cells need blood supply in order to grow. As cancer grows, it forms its own blood vessels, a process called angiogenesis. Therefore, anti-angiogenesis...
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In a nutshell This study investigated the relationship between the use of metformin (Glucophage) and prostate cancer mortality. Some background Metformin is a drug commonly used in the management of diabetes. Metformin works by suppressing glucose production in the liver and increasing the body's sensitivity to insulin. Recent studies have...
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In a nutshell This study investigated whether the biology of the cancer called mucinous histology can be used to predict the outcomes of patients with colorectal cancer. The study also evaluated the association between mucinous adenocarcinoma and microsatellite instability. Some background Mucinous histology (MH) is a microscopic observation of...
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In a nutshell This study compared the benefits of radiotherapy and tamoxifen in reducing the risk of local recurrence (return of the cancer close to initial place of origin) in patients with early breast cancer who underwent breast conserving surgery (BCS). Some background Women with early breast cancer usually have tumors that are confined...
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