In a nutshell This study investigated the effects of pregnancy following breast cancer diagnosis and treatment. Some background Nowadays, most breast cancer patients enjoy high survival rates and years of disease free quality of life. While the effects of breast cancer on fertility and pregnancy outcomes have been well researched, the effects of...
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In a nutshell This review explored the benefits of radiation therapy in the management of breast cancer. Some background Radiation therapy plays an important role in the treatment of breast cancer. Radiation therapy has been shown to decrease the risk of cancer recurrence after surgery and improve survival rates among invasive cancer patients....
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In a nutshell This study assessed the effectiveness of a brachytherapy algorithm as administered to patients with localized prostate cancer. Some background Patients with localized prostate cancer (cancer that has not spread) may be treated using a high-energy radiation that kills cancer cells (radiotherapy). Brachytherapy is a form...
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In a nutshell This study evaluated breast cancer risk and outcomes among postmenopausal women using hormone replacement therapy. Some background Progesterone and estrogen are steroid hormones that have a crucial role in female maturation and reproduction processes. The female menstrual cycle, ovulation and pregnancy are only part of the...
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In a nutshell This study evaluated preoperative magnetic resonance imaging (MRI) in the evaluation of surgical margins among rectal cancer patients. Some background Surgical removal of the tumor is the optimal treatment in the case of local rectal cancer. Removal of the intact tumor, with surrounding tissue and lymph-nodes, without leaving behind...
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In a nutshell This study investigated the use of different clinical factors in predicting pathological complete response to neoadjuvant chemoradiotherapy among rectal cancer patients. Some background Neoadjuvant therapy in rectal cancer refers to treatments given before surgery, such as chemotherapy and/or radiation treatments. Chemoradiation is...
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In a nutshell This study investigated the effectiveness of a single session of high-intensity focused ultrasound (HIFU) in patients with localized (confined) prostate cancer, as a potential curative treatment. Some background Radiotherapy or RT (the use of high-energy rays to kill cancer cells) is a widely used, non-invasive therapy for...
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In a nutshell This study evaluated the significance of sentinel-node biopsy in the outcome of melanoma patients. Some background In order to estimate melanoma spread, the risk of disease progression after surgery, and the aggressiveness of treatment necessary, a biopsy of the sentinel-node (the first lymph node draining the melanoma lesion) is...
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In a nutshell The current study examined whether the proteins versican and lumican were predictive of prognosis among colon cancer patients. Some background Colon cancer treatments vary depending on the type and stage of the disease. Patients with advanced cancer, which has invaded the surrounding lymph nodes, usually receive chemotherapy along...
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In a nutshell This study analyzed the efficacy and safety of a combination of carboplatin and S-1 in the treatment of advanced non-small cell lung cancer (NSCLC). Some background NSCLC accounts for 85% of lung cancers, and appears in two distinct histological subtypes; squamous cell carcinoma and non-squamous cell carcinoma....
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In a nutshell This study examined whether the timing of adjuvant chemotherapy affects survival among women with breast cancer. Some background Surgical resection to remove all cancerous tissue is the standard of care for the treatment of breast cancer. After surgery, many patients also undergo adjuvant treatments (additional therapy following...
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In a nutshell This study evaluated p300 as a potential prognostic marker for colorectal cancer survival. Some background Survival of colorectal cancer patients is currently estimated according to cancer staging and lymph node involvement. However, both survival and the response to treatments vary widely between patients. Therefore, new molecules...
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