In a nutshell This study investigated the relationship between the protein miR-182 and outcome of patients with non small-cell lung cancer, including the development of tumor blood supply. Some background Non small-cell lung cancer (NSCLC) is the most common type of lung cancer (80-85% of lung cancer patients) and despite improvements in treatment...
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In a nutshell This paper studied the dosage of radiotherapy in women who have had surgery for early breast cancer. Some background After surgical removal of tumour, radiation is often given to prevent relapse (return of cancer). Radiation therapy can be fractionated (dividing the total radiation into smaller doses over time). Fractionation...
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In a nutshell The authors aimed to determine whether their product could be used to determine prostate cancer-specific mortality and other outcomes after radical prostatectomy. Some background NADiA ProsVue is a device that determines the likelihood that a prostate cancer patient will experience recurrent cancer after receiving a radical...
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In a nutshell The authors aimed to determine whether African Americans were more at risk of experiencing recurrent prostate cancer or complications following a radical prostatectomy. Some background Past research has shown that African American men are 60% more likely to experience prostate cancer than white men. Previously, in men who...
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In a nutshell The authors aimed to determine whether moderate hypofractionated radiotherapy would worsen sexual function after treatment. Some background There are many options for treatment of low-risk prostate cancer (cancer with a very small likelihood of spreading), therefore side-effects and patient preferences may drive the decision of...
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In a nutshell The authors aimed to determine whether patients developed unfavorable disease features while under active surveillance. Some background Active surveillance involves no treatment. It involves close monitoring of prostate cancer patients to determine any sign of progression. It is currently recommended in low/intermediate risk...
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In a nutshell This clinical trial in New Jersey and Massachussetts (United States) aims to study anastrozole (ANAS, Arimidex) in treating aromatase inhibitor musculoskeletal symptoms in female patients with stage I-III breast cancer. The outcome to be measured is the stopping of treatment due to musculoskeletal symptoms and its association with the...
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In a nutshell This report discusses using a device to track tumor sites in follow-up biopsies in prostate cancer. Some background Biopsies (the removal of tissue from the body and examination to establish the presence of cancer) are a very important part of active surveillance (patient monitoring instead of treatment) in early prostate...
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In a nutshell This study investigated the impact of age, comorbidities (the existence of other illnesses), and tumor risk on mortality in men with early-stage prostate cancer. Some background Accurate estimation of life expectancy is essential to offering the best care to men with early-stage prostate cancer. It is known that the severity of the...
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In a nutshell This paper studied factors that might influence prostate-specific antigen (PSA) nadir levels following high-intensity ultrasound treatment in patients whose cancer has not spread beyond the prostate. Some background High-intensity focused ultrasound (HIFU) is a primary treatment in prostate cancer that targets and removes damaged or...
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In a nutshell This paper studied the characteristics of recurrence (return of cancer) in patients with triple negative breast cancer. Some background Triple negative breast cancer is a subtype of breast cancer that is associated with poorer outlook or prognosis. It means that the tumor is estrogen receptor negative (absence of estrogen...
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In a nutshell This study examined whether patients with prostate cancer who receive radiotherapy after surgery have a decreased chance of the cancer returning. Some background Surgical removal of the prostate (radical prostatectomy) is the most common treatment for patients with prostate cancer. After surgery patients can receive additional...
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