In a nutshell This study examined erectile function following treatment of prostate cancer with focal therapy. Researchers reported a return of erectile function from 6 months after focal therapy. Some background Surgery and radiation are first-line treatments for localized (confined) prostate cancer. In some cases, focal therapies are recommended...
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In a nutshell This study investigated proteins (blood factors) in patients with early-stage melanoma that identify those at a high risk of experiencing metastasis (cancer spread) after surgery. Researchers suggested that tumor stage and proteins such as vitronectin (VN) and dermcidin (DCD) levels were associated with the metastatic progression of...
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In a nutshell This study examined the risk of recurrence following early-stage non-small cell lung cancer (NSCLC) treated with surgery. The authors showed that the risk of relapse after surgery changes in a predictable way over time, where the first two years after surgery has the highest risk of relapse. They noted that the risk then declines but...
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In a nutshell The authors aimed to determine when radiotherapy should be administered, during chemotherapy-radiotherapy adjuvant treatment in patients with limited small-cell lung cancer (SCLC). They concluded that radiotherapy increases the survival rate if it is administered early during chemotherapy treatment. Some background For SCLC,...
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In a nutshell The authors aimed to determine the benefits and drawbacks of prostate cancer treatment in patients who suffer from pre-treatment urinary problems. The authors concluded that patients with pre-treatment urinary problems benefitted from prostate surgery. Some background Prostate surgery involves surgically removing the prostate...
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In a nutshell This study compared the safety and effectiveness of external beam radiation therapy (EBRT) and hypofractioned EBRT (H-EBRT) for localized prostate cancer. Researchers reported no differences in survival or disease recurrence rates between high H-EBRT and EBRT. Some background Radiation therapy is a common treatment for localized...
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In a nutshell This study analyzed the rates of disease upgrading after biopsy (tissue sample) tests in men with low-risk prostate cancer. Researchers concluded that men with low-risk prostate cancer have a very low risk of being upgraded during active surveillance. Some background Most men diagnosed with prostate cancer are categorized as low...
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In a nutshell The main objective of this study was to review all data available on focal radiotherapy (FRT) for men with early prostate cancer. The authors concluded that FRT was an option in early prostate cancer but may not be as effective in intermediate-risk tumors. Some background Radiation therapy is an important part of prostate cancer...
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In a nutshell This study investigated whether radiotherapy with lumpectomy (where only part of the breast is removed) in older women with estrogen receptor-negative (ER-) breast cancer would improve survival rates. For women over 70 years with ER- early-stage breast cancer, lumpectomy and radiotherapy improved overall survival rates and...
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In a nutshell This study investigated the outcomes of rectal cancer patients with complete or near-complete response to chemotherapy and radiation therapy (CRT) who do not undergo surgery. Researchers reported that not undergoing surgery, in selected patients, is a safe option for treatment of rectal cancer. Some background The standard...
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In a nutshell This study examined the effect of ethnicity on health outcomes with androgen deprivation therapy (ADT). Researchers reported shorter survival among African American men receiving ADT for low- or intermediate-risk prostate cancer compared to men of other ethnicities. Some background ADT is a type of hormone therapy used to treat...
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In a nutshell This study investigated the probability of melanoma-specific mortality and mortality by other causes in melanoma patients. Researchers suggested that an individualized study of each patient probability helps treatment-related decision making. Some background The majority of patients with non-metastatic (spread to other parts of the...
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