In a nutshell This review analyzed data collected from recent studies, and estimated the effect of smoking cessation after diagnosis on the outcome of lung cancer patients. Some background Smoking is known to increase the risk of developing lung cancer, as well as other life threatening medical conditions. Quitting smoking after the diagnosis of...
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In a nutshell In this study, researchers examined whether breast cancer patients who chose to have preventive removal of both breasts (bilateral mastectomy or BM) experience more post-surgery complications than patients who have removed only the cancer-affected breast (unilateral mastectomy or UM). Some background Most women with early breast...
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In a nutshell In this study, researchers examined the effect of epoetin alfa (Epogen; Procrit) on anemia (low count of red blood cells) caused by chemotherapy in breast cancer patients. Some background Breast cancer is caused by a defect that makes some breast cancer cells grow and multiply rapidly. One of the treatment options for patients with...
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In a nutshell This article evaluated which patients can benefit the most from focal therapy (treatments that target only the prostate cancer instead of the entire prostate gland) for prostate cancer. In addition, this research evaluated the effect of this treatment on sexual and bladder function. Some background Treatment which preserves as...
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In a nutshell This study compared disease free survival (the time period between the end of treatment and until the disease returns or the patient relapses) for colon cancer patients with a history of smoking versus non-smokers. Some background Cigarette smoking can increase the risk of colon cancer. However, it is not clear how prior smoking...
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In a nutshell In this trial researchers examined whether the use of neoadjuvant chemotherapy (before surgery) influenced survival or recurrence rates in women undergoing breast conserving therapy for breast cancer. Some background Neoadjuvant chemotherapy (NCT) refers to chemotherapy treatments received prior to surgery. This approach is often...
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In a nutshell This study looked at men with prostate cancer undergoing active surveillance, and tried to show which characteristics were related with an increased risk of cancer progression. Some background Prostate cancer is the uncontrolled growth and division of prostate cells. This growth can be slow and sometimes harmless, so in the...
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In a nutshell The aim of this study was to examine the association between recreational physical activity and leisure time spent sitting before and after diagnosis with survival in patients with colorectal cancer (CRC). Some background There is growing evidence that exercise is safe and well-tolerated by patients with cancer during and after the...
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In a nutshell This article looked at the benefit on survival of short term hormone therapy called androgen deprivation therapy (ADT), in combination with radiation therapy, for the treatment of patients with prostate cancer. Some background Prostate specific antigen (PSA) is a protein produced by the prostate gland. Men with a healthy...
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In a nutshell The aim of this study was to investigate the relationship between survival outcomes and specific adverse events (AEs) in patients after menopause (postmenopausal) with breast cancer treated with hormone therapy. Some background Most breast cancers grow in response to estrogen, the main female sex hormone. Therefore, hormone therapy...
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In a nutshell This article looked at the risk of adverse events such as heart disease, blood clots, strokes and fractures in patients diagnosed with prostate cancer. Some background Treatments for prostate cancer can result in numerous side effects. For example, endocrine (hormonal) treatments can result in low bone density (weak bones prone to...
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In a nutshell This study tested the effect of complete axillary lymph node removal, on survival without recurrence of the cancer (called disease free survival or DFS) in patients with breast cancer. Some background Lymph nodes are small organs which are part of the immune system. They filter fluid called lymph. Lymph can be thought of as the...
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