In a nutshell The authors aimed to determine patients who were at risk of cancer returning after surgery for prostate cancer. Some background Radical prostatectomy involves surgically removing the prostate from patients that have prostate cancer. It is used as a treatment option in early stage prostate cancer where the tumor has not spread outside...
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In a nutshell This study investigated the impact of anastomotic leakage, a major surgical complication, on the risk for rectal cancer returning. Some background The main treatment option for patients with rectal cancer is surgery. One major complication that can occur after surgery is anastomotic leakage. Generally this involves the leakage of...
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In a nutshell This paper studied the impact of endocrine therapy on sexual function in postmenopausal patients with breast cancer. Some background Endocrine therapy is used in the treatment of hormone receptor positive early breast cancer. Hormone receptor positive breast cancer is cancer which has an abundant presence of the estrogen or...
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In a nutshell This paper evaluated early discontinuation of trastuzumab (Herceptin) therapy and how cardiovascular events (disease associated with the heart and blood vessels) associated with this affect survival in older women with breast cancer. Some background Human epidermal growth factor receptor 2 (HER2) is a protein that can be found...
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In a nutshell The authors aimed to determine the effect of sun exposure on cutaneous melanoma development. Some background Cutaneous melanoma is the most common form of melanoma and can occur on all areas of the skin. One of the main factors involved in melanoma development is sun exposure. Solar elastosis, also known as actinic elastosis, is a...
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In a nutshell The authors aimed to determine whether the biopsy-based Genomic Prostate Score test could predict cancer recurrence in a racially diverse group after radical prostatectomy. Some background Active surveillance is an option taken in patients with low-risk prostate cancer (confined to the prostate) which involves no physical treatment,...
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In a nutshell The authors aimed to determine whether aspirin had any limiting effects on mortality in prostate cancer. Some background Aspirin is a drug typically used as a pain-killer. However it has been used in numerous studies to determine a relationship between aspirin and prostate cancer progression. Some studies have concluded that...
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In a nutshell The authors aimed to determine whether miR-449b could be used to predict cancer progression after radical prostatectomy. Some background miRNA is responsible for controlling such activities within the body as cell growth. As a result it plays a big role in tumor development. Recent studies have shown that miRNA can be found in the...
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In a nutshell The authors aimed to determine whether moderate hypofractionated radiotherapy would worsen sexual function after treatment. Some background There are many options for treatment of low-risk prostate cancer (cancer with a very small likelihood of spreading), therefore side-effects and patient preferences may drive the decision of...
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In a nutshell The study investigates measuring cellular CDK levels to predict the outcome of early stage-NSCLC patients. Some background Non small-cell lung cancer (NSCLC) is a common type of lung cancer that can be difficult to treat. Even early-stage NSCLC treated with surgery has a poor 5-year survival rate (65%) due...
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In a nutshell This study investigated the impact of age, comorbidities (the existence of other illnesses), and tumor risk on mortality in men with early-stage prostate cancer. Some background Accurate estimation of life expectancy is essential to offering the best care to men with early-stage prostate cancer. It is known that the severity of the...
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In a nutshell This study investigated the impact of 3 months of androgen deprivation therapy (ADT) in a group of low-risk prostate cancer patients. Some background For patients with low-risk localized prostate cancer (has not spread beyond the prostate), treatment is not recommended but the patient is carefully...
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