In a nutshell The authors aimed to determine whether specific proteins can predict bone tumors and death in patients with hormone-resistant prostate cancer. Some background In advanced prostate cancer, tumors can spread out from the initial site of cancer to other parts of the body and bones, making treatment difficult. Hormone therapy...
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In a nutshell The authors aimed to determine the 10-year outcome in patients treated with brachytherapy for localized prostate cancer. Some background Localized prostate cancer is cancer that is confined within the prostate gland. It can often be treated with brachytherapy, a form of radiation that places radioactive seeds...
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In a nutshell The authors aimed to determine how microscopic vessel invasion affects lung cancer patient outcome. Some background The visceral pleura are the membranes surrounding the lungs. In lung cancer, the presence of tumors in the visceral pleura (known as visceral pleural invasion – VPI), is a factor used in standard...
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In a nutshell This paper studied whether goserelin (Zoladex) can protect the ovaries from damage caused by chemotherapy. Some background Chemotherapy is used in the treatment of breast cancer but it can damage to the ovaries. This can lead to infertility. Goserelin is a gonadotropin releasing hormone agonist and works to suppress production...
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In a nutshell The authors aimed to determine patient and cancer outcome following treatment with pelvic lymph node dissection and robot-assisted prostate surgery. Some background In some prostate cancer patients tumors can spread into the lymph nodes (sites that hold cells used to fight infection). A pelvic lymph node dissection is used to...
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In a nutshell The authors aimed to determine patient outcome after salvage prostate surgery using patient information. Some background Prostate surgery is a common cancer treatment that involves surgically removing the prostate gland. Salvage prostate surgery is carried out after radiation therapy (involves directing a beam of radiation at the...
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In a nutshell The authors aimed to determine whether levels of YAP protein could predict the success of treatment in patients with lung cancer. Some background YAP protein is a protein active in many cancers that can have a positive or negative effect depending on the location. When YAP protein is present in the nucleus (brain of the cancer...
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In a nutshell This study investigated the effects of hormone therapy given before brachytherapy (a form of radiation therapy) on the survival of prostate cancer patients with at least one risk factor for coronary artery disease compared to those with no risk factors. Some background Quite often, hormone therapy such as anti-androgen therapy...
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In a nutshell The authors aimed to determine if a new risk classification system could help determine treatment and outcome in individuals with intermediate-risk prostate cancer. Some background External-beam radiation therapy (EBRT) is a form of treatment that involves the application of an external radiation source focused at the site of...
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In a nutshell This study investigated whether statins (such as Lipitor, Livalo) can improve survival for colorectal cancer patients. Some background Statins are a class of drug used to lower cholesterol. They are used to prevent heart disease in patients who are at high risk. Recent evidence suggests that statins also slow cell growth, stop new...
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In a nutshell The authors aimed to determine the effects of sildenafil citrate in improving sexual function after radiotherapy. Some background Radiotherapy is the use of high-energy rays to target and cure cancer with minimal damage to normal cells and is a common treatment option in prostate cancer. It can be given from outside the body or from...
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In a nutshell The authors aimed to determine the impact of obesity on long-term cancer outcomes in patients after prostate surgery. Some background Prostate surgery is the standard treatment in patients with prostate cancer confined within the prostate gland. This involves surgically removing the prostate. Obesity is classified as having a body...
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