In a nutshell The authors determined the risk factors that led to disease reclassification (change in grade/status of the disease) in prostate cancer patients under active surveillance. Some background Active surveillance is common in early-stage prostate cancer management. It involves active monitoring of patients for any changes in symptoms or...
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In a nutshell The authors aimed to determine the risks of cancer recurrence (the cancer returns) between the time of hormone or endocrine therapy and the 10 years following. Some background Endocrine therapy is used as treatment against particular cancers that may grow in response to hormones natural to our body. This includes hormone...
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In a nutshell The authors aimed to determine both the effectiveness and toxicity of a type of chemotherapy treatment for breast cancer. Some background Adjuvant chemotherapy is a course of chemotherapy that patients often receive after their main treatment. Chemotherapy can reduce the risk of cancer recurrence (the cancer returns) and improve...
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In a nutshell This study compared two treatments for early-stage non-small cell lung cancer (NSCLC): surgery and a radiosurgery treatment known as SBRT (stereotactic body radiotherapy). Some background Currently, the standard treatment protocol for early-stage (has not spread beyond the lungs) non-small cell lung...
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In a nutshell The authors aimed to assess the benefits of prolonged use of hormone therapy to treat breast cancer in women undergoing the menopause transition. Some background Endocrine or hormone therapy is a type of treatment used to fight cancer cells with the presence of hormone receptors (HR+). Hormones natural to our body such as estrogen or...
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In a nutshell The authors aimed to evaluate the prognostic (disease outlook) effect of the presence of certain hormone receptors on cancer cells. Some background Breast cancer is classified into different subtypes depending on the presence or absence of certain receptors (proteins found on the surface of the cancer cells). Breast cancer...
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In a nutshell The authors determined the effect of cryoablation in locally recurrent (return of cancer to or near the original site) prostate cancer following radiotherapy. Some background Radiotherapy is a common treatment used in prostate cancer. It involves directing a beam of radiation at the tumor site in order to kill cancer...
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In a nutshell The authors aimed to distinguish whether the characteristics of breast cancer could depend on the focality of the tumor. Some background Breast cancer can be characterized as 'unifocal', 'multifocal and 'multicentric'. This refers to the number of areas in which the cancer can be found (focality); unifocal...
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In a nutshell The authors aimed to determine the risks of developing cardiac or heart problems while being treated with trastuzumab (Herceptin) for breast cancer. Some background Trastuzumab is a form of endocrine or hormone therapy used to treat patients with human epidermal growth factor 2 positive (HER2+) breast cancer. Since the approval of...
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In a nutshell The authors aimed to determine factors associated with weight gain in patients who received hormone therapy. Some background Hormone therapy is a common treatment used in prostate cancer. It targets hormones active in prostate cancer, such as testosterone. Some patients might experience weight gain following...
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In a nutshell This study looked at the association between the lymphocyte-monocyte ratio (LMR) in patients' blood and their lung cancer outcome. Some background Lung cancer is one of the most common cancers worldwide. Despite improvements in treatment outcomes are still quite poor. Therefore early detection and treatment is...
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In a nutshell The authors aimed to determine the link between hormone therapy and metabolic syndrome in prostate cancer patients. Some background Hormone therapy is a common treatment used in prostate cancer management. It blocks the male sex hormones active in prostate cancer, such as testosterone. In some patients hormone therapy can...
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