In a nutshell This study evaluated the effectiveness and safety outcomes of atezolizumab (Tecentriq) given before surgery for the treatment of patients with non-small cell lung cancer (NSCLC). The data showed that atezolizumab given before surgery was safe and effective for patients with NSCLC. Some background Non-small cell lung cancer (NSCLC)...
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Does Oncotype DX testing reduce the use of chemotherapy in patients with estrogen receptor positive breast cancer?
In a nutshell In this study, researchers evaluated whether a genetic test called Oncotype DX, reduced the use of chemotherapy treatment for patients with node-positive and estrogen-receptor positive breast cancer. Some background Some breast cancers grow in response to estrogen, the main female sex hormone, via their receptor (a protein found on...
Read MoreRisk of Heart Failure after Anthracycline (Adriamycin/Daunomycin) and Trastuzumab (Herceptin) Treatments for Breast Cancer
In a nutshell This study evaluated the risk of heart disease associated with two commonly prescribed treatments for breast cancer. The main finding was that Trastuzumab (Herceptin) and Anthracycline (Adriamycin/Daunomycin) treatments are associated with a higher risk of heart failure or ‘cardiomyopathy’. Some background Anthracyclines...
Read MoreBenefits of post-operative chemotherapy according to hormone receptor status
In a nutshell This study compared the benefits of chemotherapy according to hormone receptor status. The main findings were: In cancers without hormone receptors, the benefits of adding chemotherapy were significant; In cancers with hormone receptors, chemotherapy only offered modest improvement. Some background Some...
Read MoreExtended versus Targeted Lymph Node Surgery for Invasive Breast Cancer
In a nutshell This study compared survival rates for two surgical strategies in treating invasive breast cancer. The main finding was that the targeted Sentinel Lymph Node Dissection (SLND) procedure was just as effective as the traditional Axillary Lymph Node Dissection (ALND) surgery. Some background Lymph from the breast drains...
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