In a nutshell This study compared the effectiveness of aromatase inhibitors (AIs) versus tamoxifen (Nolvadex) for the treatment of premenopausal patients with estrogen receptor-positive (ER+) early-stage breast cancer (BC) treated with ovarian suppression. The data showed that AIs significantly reduced the risk of BC recurrence compared...Read More
Current stage-Stage 0 Posts on Medivizor
Evaluating the effectiveness of antiresorptive drugs on bone mineral density in postmenopausal women with early-stage breast cancer receiving treatment with aromatase inhibitors.
In a nutshell This study evaluated the effectiveness of antiresorptive drugs on bone mineral density (BMD) in postmenopausal women with early-stage breast cancer (BC) receiving treatment with aromatase inhibitors (AIs). The data showed that denosumab (Prolia) and zoledronic acid (Aclasta) were the most effective antiresorptive treatment options to...Read More
Extended therapy with letrozole for 5 years improves survival outcomes in postmenopausal patients with hormone positive early-stage breast cancer.
In a nutshell This study compared the effectiveness and safety of extended therapy with letrozole (LET; Femara) for 5 years versus the standard therapy of 2-3 years for the treatment of postmenopausal women with early-stage breast cancer (BC). The data showed that extended treatment with LET for 5 years significantly improved the survival outcomes...Read More
Effects of adherence to homone therapy after surgery and radiation on the outcomes of older patients with early-stage breast cancer
In a nutshell This study aimed to investigate the effects of adherence to hormonal therapy (HT) and radiation on the outcomes of older patients with early-stage breast cancer (BC). This study concluded that the lack of adherence to HT and omitting radiation can lead to poorer outcomes for these...Read More
In a nutshell The authors investigated whether intra-operative electron radiotherapy (IOERT) boost reduces breast cancer recurrence compared to standard radiotherapy. They found that IOERT slightly reduced cancer recurrence compared to standard external beam radiotherapy (EBRT). Some background Breast cancer is the most commonly diagnosed...Read More
In a nutshell The aim of this study was to investigate the role of chemotherapy (CT) after surgery in patients with rectal cancer. The study suggests that CT after surgery could improve patient outcomes. Some background Rectal cancer can be treated with surgery to remove the tumor. In general, patients are given CT before the...Read More
Survival of patients with rectal cancer followed-up by the watch and wait method after chemoradiotherapy
In a nutshell This study investigated the outcomes of patients with rectal cancer who were followed up with the watch and wait method after chemoradiotherapy (CRT). Researchers suggested that this strategy can effectively identify patients who can have a less frequent follow-up if they maintain response for the first 3 years...Read More
In a nutshell This article looked at the use of partial breast irradiation (PBI) versus whole-breast irradiation (WBI) as a treatment for breast cancer (BC). The authors found that PBI offered similar results when compared to WBI. Some background BC remains one of the most common forms of cancer found in women. Standard care for BC remains...Read More
Does the histological grade of early stage breast cancer effect outcomes of older women treated with breast conserving surgery?
In a nutshell This article was carried out to look at how histological grade (HG) impacts the outcomes of older women with early-stage (ES) breast cancer (BC) treated with breast-conserving therapy (BCS) with or without radiotherapy (RT). The authors found that the treatment of ESBC without RT resulted in a lower cancer-specific survival...Read More
Looking for patients with breast reconstructions following breast surgery to trial a short radiation therapy
In a nutshell This trial is looking to examine the use of radiation on a shorter schedule of 5 days in a row is a safe and effective way to prevent breast cancer (BC) from coming back in people who have had a mastectomy (surgical removal of the breast). The main outcomes that are to be measured are local and regional disease recurrence. This trial is to...Read More
Comparing breast-conserving surgery and breast-removal surgery after chemotherapy in patients with breast cancer
In a nutshell This study compared the effectiveness of breast-conserving surgery (BCS) to mastectomy (breast-removal surgery) after chemotherapy in patients with breast cancer. The authors found that BCS does not result in a lower survival in these patients. Some background BC is one of the most common forms of cancer in women. Standard care...Read More
In a nutshell The study evaluated the contribution of chemotherapy on cancer-related cognitive impairment (CRCI) reported by women with early breast cancer. The authors found that chemotherapy added to hormonal therapy caused early and short-term CRCI in such patients, compared to hormonal therapy alone. Some background CRCI refers to problems in...Read More