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Aromatase inhibitors versus tamoxifen for premenopausal women with hormone positive early-stage breast cancer treated with ovarian suppression.

Aromatase inhibitors versus tamoxifen for premenopausal women with hormone positive early-stage breast cancer treated with ovarian suppression.

Posted by on Jun 26, 2022 in Breast cancer | 0 comments

In a nutshell This study compared the effectiveness of aromatase inhibitors (AIs) versus tamoxifen (Nolvadex) for the treatment of premenopausal patients with estrogen receptor-positive (ER+) early-stage breast cancer (BC) treated with ovarian suppression. The data showed that AIs significantly reduced the risk of BC recurrence compared...

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Evaluating the effectiveness of antiresorptive drugs on bone mineral density in postmenopausal women with early-stage breast cancer receiving treatment with aromatase inhibitors.

Evaluating the effectiveness of antiresorptive drugs on bone mineral density in postmenopausal women with early-stage breast cancer receiving treatment with aromatase inhibitors.

Posted by on May 31, 2022 in Breast cancer | 0 comments

In a nutshell This study evaluated the effectiveness of antiresorptive drugs on bone mineral density (BMD) in postmenopausal women with early-stage breast cancer (BC) receiving treatment with aromatase inhibitors (AIs). The data showed that denosumab (Prolia) and zoledronic acid (Aclasta) were the most effective antiresorptive treatment options to...

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Extended therapy with letrozole for 5 years improves survival outcomes in postmenopausal patients with hormone positive early-stage breast cancer.

Extended therapy with letrozole for 5 years improves survival outcomes in postmenopausal patients with hormone positive early-stage breast cancer.

Posted by on Oct 24, 2021 in Breast cancer | 0 comments

In a nutshell This study compared the effectiveness and safety of extended therapy with letrozole (LET; Femara) for 5 years versus the standard therapy of 2-3 years for the treatment of postmenopausal women with early-stage breast cancer (BC). The data showed that extended treatment with LET for 5 years significantly improved the survival outcomes...

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Effects of adherence to homone therapy after surgery and radiation on the outcomes of older patients with early-stage breast cancer

Effects of adherence to homone therapy after surgery and radiation on the outcomes of older patients with early-stage breast cancer

Posted by on Jun 13, 2021 in Breast cancer | 0 comments

In a nutshell This study aimed to investigate the effects of adherence to hormonal therapy (HT) and radiation on the outcomes of older patients with early-stage breast cancer (BC).   This study concluded that the lack of adherence to HT and omitting radiation can lead to poorer outcomes for these...

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Does radiotherapy with electrons boost during surgery reduce the risk of breast cancer recurrence?

Does radiotherapy with electrons boost during surgery reduce the risk of breast cancer recurrence?

Posted by on May 16, 2021 in Breast cancer | 0 comments

In a nutshell The authors investigated whether intra-operative electron radiotherapy (IOERT) boost reduces breast cancer recurrence compared to standard radiotherapy. They found that IOERT slightly reduced cancer recurrence compared to standard external beam radiotherapy (EBRT). Some background Breast cancer is the most commonly diagnosed...

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Survival of patients with rectal cancer followed-up by the watch and wait method after chemoradiotherapy

Survival of patients with rectal cancer followed-up by the watch and wait method after chemoradiotherapy

Posted by on Apr 21, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the outcomes of patients with rectal cancer who were followed up with the watch and wait method after chemoradiotherapy (CRT). Researchers suggested that this strategy can effectively identify patients who can have a less frequent follow-up if they maintain response for the first 3 years...

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Comparing partial breast irradiation and whole breast irradiation in patients with breast cancer

Comparing partial breast irradiation and whole breast irradiation in patients with breast cancer

Posted by on Feb 14, 2021 in Breast cancer | 0 comments

In a nutshell This article looked at the use of partial breast irradiation (PBI) versus whole-breast irradiation (WBI) as a treatment for breast cancer (BC). The authors found that PBI offered similar results when compared to WBI.  Some background BC remains one of the most common forms of cancer found in women. Standard care for BC remains...

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Does the histological grade of early stage breast cancer effect outcomes of older women treated with breast conserving surgery?

Does the histological grade of early stage breast cancer effect outcomes of older women treated with breast conserving surgery?

Posted by on Jan 31, 2021 in Breast cancer | 0 comments

In a nutshell This article was carried out to look at how histological grade (HG) impacts the outcomes of older women with early-stage (ES) breast cancer (BC) treated with breast-conserving therapy (BCS) with or without radiotherapy (RT). The authors found that the treatment of ESBC without RT resulted in a lower cancer-specific survival...

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Looking for patients with breast reconstructions following breast surgery to trial a short radiation therapy

Looking for patients with breast reconstructions following breast surgery to trial a short radiation therapy

Posted by on Jan 28, 2021 in Breast cancer | 0 comments

In a nutshell This trial is looking to examine the use of radiation on a shorter schedule of 5 days in a row is a safe and effective way to prevent breast cancer (BC) from coming back in people who have had a mastectomy (surgical removal of the breast). The main outcomes that are to be measured are local and regional disease recurrence. This trial is to...

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Comparing breast-conserving surgery and breast-removal surgery after chemotherapy in patients with breast cancer

Comparing breast-conserving surgery and breast-removal surgery after chemotherapy in patients with breast cancer

Posted by on Nov 5, 2020 in Breast cancer | 0 comments

In a nutshell This study compared the effectiveness of breast-conserving surgery (BCS) to mastectomy (breast-removal surgery) after chemotherapy in patients with breast cancer. The authors found that BCS does not result in a lower survival in these patients. Some background BC is one of the most common forms of cancer in women. Standard care...

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Evaluating the effects of chemotherapy on cognitive function in patients with early breast cancer

Evaluating the effects of chemotherapy on cognitive function in patients with early breast cancer

Posted by on Jun 28, 2020 in Breast cancer | 0 comments

In a nutshell The study evaluated the contribution of chemotherapy on cancer-related cognitive impairment (CRCI) reported by women with early breast cancer. The authors found that chemotherapy added to hormonal therapy caused early and short-term CRCI in such patients, compared to hormonal therapy alone. Some background CRCI refers to problems in...

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