In a nutshell The study evaluated the long-term effectiveness of accelerated partial breast irradiation (ABPI) using multicatheter brachytherapy (BT) with whole-breast irradiation (WBI) in patients with early breast cancer (BC). The study found that ABPI using multicatheter BT was similarly effective with fewer serious side effects compared to...
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Evaluating the impact of fertility preservation on breast cancer and pregnancy outcomes in young women with breast cancer.
In a nutshell This study evaluated the impact of fertility preservation with ovarian stimulation on breast cancer and pregnancy outcomes in young women with breast cancer (BC). The data showed that fertility preservation was safe and did impact BC outcomes. Some background Breast cancer (BC) is one of the most common cancers affecting women...
Read MoreEvaluating the role of radiotherapy in HER2+ early-stage breast cancer after breast-conserving surgery
In a nutshell The study evaluated the effectiveness of radiotherapy (RT) in patients with HER2+ early-stage breast cancer (BC) after breast-conserving surgery (BCS). The study found that RT improved the survival rates of these patients, especially for those high-risk. Some background BC is categorized based on the absence or...
Read MoreAromatase inhibitors versus tamoxifen for premenopausal women with hormone positive early-stage breast cancer treated with ovarian suppression.
In a nutshell This study compared the effectiveness of aromatase inhibitors (AIs) versus tamoxifen (Nolvadex) for the treatment of premenopausal patients with estrogen receptor-positive (ER+) early-stage breast cancer (BC) treated with ovarian suppression. The data showed that AIs significantly reduced the risk of BC recurrence compared...
Read MoreEvaluating the effectiveness of antiresorptive drugs on bone mineral density in postmenopausal women with early-stage breast cancer receiving treatment with aromatase inhibitors.
In a nutshell This study evaluated the effectiveness of antiresorptive drugs on bone mineral density (BMD) in postmenopausal women with early-stage breast cancer (BC) receiving treatment with aromatase inhibitors (AIs). The data showed that denosumab (Prolia) and zoledronic acid (Aclasta) were the most effective antiresorptive treatment options to...
Read MoreExtended therapy with letrozole for 5 years improves survival outcomes in postmenopausal patients with hormone positive early-stage breast cancer.
In a nutshell This study compared the effectiveness and safety of extended therapy with letrozole (LET; Femara) for 5 years versus the standard therapy of 2-3 years for the treatment of postmenopausal women with early-stage breast cancer (BC). The data showed that extended treatment with LET for 5 years significantly improved the survival outcomes...
Read MoreEffects of adherence to homone therapy after surgery and radiation on the outcomes of older patients with early-stage breast cancer
In a nutshell This study aimed to investigate the effects of adherence to hormonal therapy (HT) and radiation on the outcomes of older patients with early-stage breast cancer (BC). This study concluded that the lack of adherence to HT and omitting radiation can lead to poorer outcomes for these...
Read MoreDoes radiotherapy with electrons boost during surgery reduce the risk of breast cancer recurrence?
In a nutshell The authors investigated whether intra-operative electron radiotherapy (IOERT) boost reduces breast cancer recurrence compared to standard radiotherapy. They found that IOERT slightly reduced cancer recurrence compared to standard external beam radiotherapy (EBRT). Some background Breast cancer is the most commonly diagnosed...
Read MoreHow beneficial is chemotherapy after surgery for patients with rectal cancer?
In a nutshell The aim of this study was to investigate the role of chemotherapy (CT) after surgery in patients with rectal cancer. The study suggests that CT after surgery could improve patient outcomes. Some background Rectal cancer can be treated with surgery to remove the tumor. In general, patients are given CT before the...
Read MoreSurvival of patients with rectal cancer followed-up by the watch and wait method after chemoradiotherapy
In a nutshell This study investigated the outcomes of patients with rectal cancer who were followed up with the watch and wait method after chemoradiotherapy (CRT). Researchers suggested that this strategy can effectively identify patients who can have a less frequent follow-up if they maintain response for the first 3 years...
Read MoreComparing partial breast irradiation and whole breast irradiation in patients with breast cancer
In a nutshell This article looked at the use of partial breast irradiation (PBI) versus whole-breast irradiation (WBI) as a treatment for breast cancer (BC). The authors found that PBI offered similar results when compared to WBI. Some background BC remains one of the most common forms of cancer found in women. Standard care for BC remains...
Read MoreDoes the histological grade of early stage breast cancer effect outcomes of older women treated with breast conserving surgery?
In a nutshell This article was carried out to look at how histological grade (HG) impacts the outcomes of older women with early-stage (ES) breast cancer (BC) treated with breast-conserving therapy (BCS) with or without radiotherapy (RT). The authors found that the treatment of ESBC without RT resulted in a lower cancer-specific survival...
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