In a nutshell This study investigated the impact of metabolic syndrome on treatment outcome with abiraterone acetate (Zytiga) for hormone-resistant prostate cancer. Researchers concluded that metabolic syndrome has an adverse outcome on disease progression in advanced prostate cancer. Some background Hormone therapy is a common treatment used in...
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In a nutshell This study examined prostate surgery as a treatment option for prostate cancer with lymph node involvement. Researchers reported that prostate surgery alone is associated with good treatment outcomes in men with low levels of prostate cancer spread. Some background In some patients, prostate cancer cells can spread to local lymph...
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In a nutshell This study examined the benefits of prostate surgery among older men with high-risk prostate cancer and additional medical conditions. Researchers concluded that prostate surgery is a suitable treatment option for older high-risk prostate cancer patients with few additional medical conditions. Some background Surgical removal of the...
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In a nutshell This study examined the potential benefit of early intensive hormonal therapy (combined androgen blockade) in men with high-risk local prostate cancer, given before surgery. Researchers concluded that intensive hormone therapy may be more effective than standard treatment in reducing androgen levels, but seldom results in complete tumor...
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In a nutshell The authors aimed to determine whether patients with T2c prostate tumors had an intermediate or high-risk disease. Some background Prostate cancer can be classified as low, intermediate or high-risk. This is based on the risk factors present. Risk factors include high prostate specific antigen levels (PSA – protein...
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In a nutshell The authors aimed to determine whether hormone therapy alone or hormone therapy combined with radiation improved survival in prostate cancer patients. Some background Hormone therapy is a type of prostate cancer treatment that targets the male sex hormones active in prostate cancer, such as testosterone. Radiation therapy...
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In a nutshell The authors aimed to determine patient and cancer outcome following treatment with pelvic lymph node dissection and robot-assisted prostate surgery. Some background In some prostate cancer patients tumors can spread into the lymph nodes (sites that hold cells used to fight infection). A pelvic lymph node dissection is used to...
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In a nutshell The authors aimed to determine long-term survival in patients with adenocarcinoma treated with radical prostatectomy. Some background Adenocarcinoma is the most common type of prostate cancer. It starts in the prostate gland and requires early treatment to prevent the cancer spreading. Radical prostatectomy is a form of treatment...
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In a nutshell The authors aimed to determine cancer-related and quality-of-life outcomes when treated with two different types of robot-assisted laparoscopic radical prostatectomy. Some background Robot-assisted laparoscopic radical prostatectomy (removal of the prostate) (RALP) is a robotic technique that allows accurate and careful removal...
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In a nutshell This paper investigates measurement of the levels of the protein prostate-specific-antigen (PSA) as a predictor of cancer returning when the patient is treated with neoadjuvant androgen deprivation therapy and radiotherapy. Some background Prostate cancer patients have been shown to have higher rates of biochemical relapse-free...
Read MoreIn a nutshell This phase III trial is studying prostate radiation therapy to see how well it works compared with short-term androgen deprivation therapy given together with pelvic lymph node radiation therapy with or without prostate radiation therapy in treating patients with a rising prostate specific antien (PSA) after prostatectomy (surgery...
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