Current disease status-Recurrent leukemia - Page 5 of 8 Posts on Medivizor
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Current disease status-Recurrent leukemia Posts on Medivizor

Is mismatched donor stem cell transplantation an effective treatment in high-risk relapse of ALL?

Is mismatched donor stem cell transplantation an effective treatment in high-risk relapse of ALL?

Posted by on Jun 25, 2018 in Leukemia | 0 comments

In a nutshell This study looked at the effectiveness of mismatched donor stem cell transplantation (SCT) for treating children with high-risk relapse of acute lymphoblastic leukemia (ALL). Researchers found that mismatched donor SCT was useful but not as effective as matched donor SCT in children with high-risk ALL. Some background Acute lymphoblastic...

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Does ibrutinib pre-treatment affect the outcomes of alloHCT for patients with CLL?

Does ibrutinib pre-treatment affect the outcomes of alloHCT for patients with CLL?

Posted by on May 31, 2018 in Leukemia | 0 comments

In a nutshell This study investigated the safety and effectiveness of alloHCT (allogeneic hematopoietic stem cell transplantation) in patients with chronic lymphocytic leukemia (CLL) pre-treated with ibrutinib (Imbruvica). This study concluded that ibrutinib does not affect the safety of alloHCT. Some background Ibrutinib has become the standard of...

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Is thiotepa-based reduced-intensity conditioning effective before cord blood stem cell transplantation?

Is thiotepa-based reduced-intensity conditioning effective before cord blood stem cell transplantation?

Posted by on May 31, 2018 in Leukemia | 0 comments

In a nutshell This study examined the effectiveness of thiotepa-based RIC in leukemia and lymphoma patients undergoing stem cell transplantation. The authors concluded that this treatment improved outcomes compared to standard RIC. Some background Before undergoing stem cell transplantation, patients with lymphoma or leukemia must undergo conditioning...

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Can chronic myeloid leukemia patients discontinue dasatinib after a year of deep molecular response?

Can chronic myeloid leukemia patients discontinue dasatinib after a year of deep molecular response?

Posted by on May 12, 2018 in Leukemia | 0 comments

In a nutshell This study aimed to investigate if dasatinib could be successfully discontinued in chronic myeloid leukemia patients who were receiving it as a second line treatment after a year of deep molecular response. This study concluded that it was possible to discontinue dasatinib use in this group of patients. Some background Imatinib...

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Sorafenib to improve outcome after transplant for patients with FLT3-ITD acute myeloid leukemia

Sorafenib to improve outcome after transplant for patients with FLT3-ITD acute myeloid leukemia

Posted by on May 1, 2018 in Leukemia | 0 comments

In a nutshell This study aimed to evaluate the effect of sorafenib (Nexavar) on the outcomes of patients with acute myeloid leukemia (AML) with FMS-like tyrosine kinase 3 (FLT3)–internal tandem duplication (ITD) undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). This study concluded that sorafenib before or after...

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How safe and effective is ponatinib for chronic phase chronic myeloid leukemia patients?

How safe and effective is ponatinib for chronic phase chronic myeloid leukemia patients?

Posted by on Apr 18, 2018 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the effectiveness and safety of ponatinib (Iclusig) for patients with chronic phase chronic myelogenous leukemia. This study concluded that ponatinib is safe and effective in this group of patients. Some background The Philadelphia chromosome (BCR-ABL1) is found in almost all patients with chronic...

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A new option for chronic myeloid leukemia patients who have an intolerance to TKIs

A new option for chronic myeloid leukemia patients who have an intolerance to TKIs

Posted by on Mar 27, 2018 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the safety and effectiveness of nilotinib (Tasigna) in patients with chronic phase chronic myeloid leukemia who have an intolerance to other tyrosine kinase inhibitors. This study concluded that this group of patients can be treated with nilotinib and it can lead to deep molecular responses. Some background...

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Risk factors that influence outcomes for acute leukemia patients with relapse after hematopoietic stem cell transplant.

Risk factors that influence outcomes for acute leukemia patients with relapse after hematopoietic stem cell transplant.

Posted by on Mar 17, 2018 in Leukemia | 0 comments

In a nutshell This study aimed to investigate risk factors that influence the outcome of acute leukemia patients who experience relapse after hematopoietic stem cell transplant. This study concluded that certain factors, such as older age and not acheiving remission after relapse treatment, are associated with worse survival outcomes. Some...

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17p deletion and 8q24 gain: Two chromosomal abnormalities that can predict outcomes

17p deletion and 8q24 gain: Two chromosomal abnormalities that can predict outcomes

Posted by on Mar 11, 2018 in Leukemia | 0 comments

In a nutshell This study examined causes and outcomes of a chromosomal abnormality known as 17p deletion in chronic lymphocytic leukemia (CLL). Researchers reported poor outcomes for patients that have both 17p deletion and 8q24 gain. Some background Certain genetic changes in CLL can make it more difficult to treat. Changes in the chromosomes, such...

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