In a nutshell The authors aimed to assess the value and safety of eribulin mesylate (Halaven, a chemotherapy drug) when used to treat women with recurrent (the cancer has returned) or metastatic (the cancer has spread) breast cancer. Some background Human epidermal growth factor 2 negative (HER2-, not dependent on HER2 for growth) breast...
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Bone biomarkers predicting prostate cancer survival
In a nutshell The authors determined the value of bone biomarkers in predicting poor survival in patients with hormone resistant prostate cancer. Some background Hormone therapy is a common treatment for prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone. Some patients can develop...
Read MoreSequencing treatments in stage 4 colorectal cancer
In a nutshell This review looked at the effectiveness of angiogenesis inhibitors (such as bevacizumab [Avastin] or aflibercept [Eylea]) in colorectal cancer, and in what sequence these treatments should be used. Some background Angiogenesis inhibitors (AIs) prevent the formation of new blood vessels necessary for tumor growth. They are often used...
Read MoreIs afatinib effective in non-small cell lung cancer that has spread?
In a nutshell This review looked at the effectiveness and safety of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor, afatinib (Gilotrif) in patients with non-small cell lung cancer (NSCLC) that has spread from its original site. Some background Many NSCLC patients have a mutated (abnormal) EGFR gene, which can increase...
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