In a nutshell The authors determined the benefit of measuring tumor cells in the blood for the treatment of advanced melanoma. Some background Treatment options for advanced melanoma include targeted therapy (targeting specific genes or proteins) and immunotherapy (using the body’s own immune system to fight cancer)....
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In a nutshell This study compared at a new radiotherapy technique to common radiotherapy treatments for Non-small cell lung cancer patients (NSCLC). Some background Radiation therapy uses high energy radiation to kill cancer cells by damaging their DNA (the genetic material found in cells). Radiation therapy usually involves low...
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In a nutshell The authors analyzed the effect of radium-223 dichloride (Xofigo) in treating castratation-resistant prostate cancer with symptoms of bone tumors. Some background Hormone therapy is a common treatment in prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone. Some...
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In a nutshell This study looked at the changes in the condition of patients with colorectal cancer who had surgery to remove their tumors. Some background Studies have shown that surgical removal of tumors (known as resection) is associated with a positive outlook in survival for patients with colorectal cancer. This is true for patients...
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In a nutshell The authors analyzed the effectiveness and safety of retreatment with ipilimumab (Yervoy) in patients with advanced melanoma. Some background The survival rate in advanced melanoma is poor. Ipilimumab, an immunotherapy (treatment that uses the body’s own immune system to fight cancer), is an...
Read MoreIn a nutshell The authors analyzed the factors that predict the return of melanoma (recurrence) and the survival of recurrent melanoma patients following a negative diagnostic report. Some background One of the most important factors that predict the possibility of melanoma recurrence is the status of sentinel lymph node (SLN). SLN is...
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In a nutshell The authors determined the effect of metformin (Glucophage) on cancer recurrence (return of cancer) and overall survival in prostate cancer patients. Some background Metformin is a drug used to treat diabetes by regulating blood sugar levels. However, numerous studies have shown that metformin may have...
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In a nutshell The authors analyzed the relationship between melanoma deaths and sentinel lymph node (SLN) metastases (spread of cancer) in melanoma patients of all ages. Some background SLN is the first lymph node or nodes (tiny, bean-shaped organs that help fight infection) cancer cells spread in to. The presence of SLN is...
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In a nutshell This study examined the effectiveness of a blood test (commercially known as VeriStrat) used for predicting the benefit of EGFR inhibitors in non-small cell lung cancer. Some background The epidermal growth factor receptor (EGFR) is involved in cell growth. Increased levels of EGFR can increase non-small cell lung...
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In a nutshell The authors examined the safety of ipilimumab (Yervoy) and the associated skin-related adverse events in the treatment of melanoma. Some background In advanced melanoma, cancer spreads from deep within the skin to other parts of the body. Ipilimumab, an immunotherapy (treatment that uses body’s own...
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In a nutshell The authors aimed to determine factors associated with weight gain in patients who received hormone therapy. Some background Hormone therapy is a common treatment used in prostate cancer. It targets hormones active in prostate cancer, such as testosterone. Some patients might experience weight gain following...
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In a nutshell The authors evaluated the outcomes of stereotactic body radiation therapy (SBRT; very precise radiation therapy) for isolated lung metastasis (cancer that has only spread to the lungs) arising after surgery for lung tumors. Some background Lung metastasis is one of the most common problems in cancer irrespective of the origin of...
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